The first report of disseminated Nocardia concava infection, in an immunocompromised patient, in South Korea

Abstract A new Nocardia species, N. concava , was first reported in Japan in 2005. To date, there have been only 3 case reports of N. concava infection worldwide (2 in Japan and 1 in China), and only 1 of these reports has detailed the clinical characteristics of N. concava, in China. Here we report...

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Bibliographic Details
Published in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2012, Vol.18 (5), p.764-766
Main Authors: Lee, Seung-Hoon, Lee, Sang-Oh, Choi, Sang-Ho, Kim, Yang-Soo, Woo, Jun-Hee, Kim, Sung-Han, Sung, Heungseop
Format: Article
Language:English
Subjects:
Abscess - drug therapy
Abscess - immunology
Abscess - microbiology
Abscess - pathology
Anti-Bacterial Agents - therapeutic use
Arm - microbiology
Arm - pathology
Case Report
Deltoid Muscle - microbiology
Deltoid Muscle - pathology
Disseminated nocardiosis
Hematology, Oncology and Palliative Medicine
Humans
Immunocompromised Host
Infectious Diseases
Korea
Male
Medical Microbiology
Medicine
Medicine & Public Health
Middle Aged
Nocardia
Nocardia concava
Nocardia Infections - diagnosis
Nocardia Infections - drug therapy
Nocardia Infections - immunology
Nocardia Infections - microbiology
Republic of Korea
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
Virology
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Summary:Abstract A new Nocardia species, N. concava , was first reported in Japan in 2005. To date, there have been only 3 case reports of N. concava infection worldwide (2 in Japan and 1 in China), and only 1 of these reports has detailed the clinical characteristics of N. concava, in China. Here we report the first case of disseminated infection caused by N. concava– in a patient with a history of glucocorticoid use–in South Korea. Species identification of N. concava was done with 16S rRNA sequencing and was confirmed by biochemical tests using urea, xanthine, tyrosine, and hypoxanthine decomposition. The patient was successfully treated with trimethoprim–sulfamethoxazole.
ISSN:1341-321X
1437-7780
DOI:10.1007/s10156-011-0364-5