Carbon Dot-Based Inorganic-Organic Nanosystem for Two-Photon Imaging and Biosensing of pH Variation in Living Cells and Tissues

A carbon dot (C‐Dot)‐based two‐photon fluorescent probe has been developed for the monitoring of pH changes across a broad range with high sensitivity and selectivity. The inorganic–organic probe also shows good biocompatibility and cell permeability, and thus can be successfully applied in bioimagi...

Full description

Saved in:
Bibliographic Details
Published in:Advanced materials (Weinheim) 2012-11, Vol.24 (43), p.5844-5848
Main Authors: Kong, Biao, Zhu, Anwei, Ding, Changqin, Zhao, Xiaoming, Li, Bo, Tian, Yang
Format: Article
Language:English
Subjects:
Animals
Biosensing Techniques
biosensors
Carbon - chemistry
carbon dots
Cell Line, Tumor
cells
Fluorescent Dyes - chemistry
Humans
Hydrogen-Ion Concentration
Mice
Mice, Nude
Microscopy, Confocal
Nanostructures - chemistry
Neoplasms - pathology
Photons
tissues
Transplantation, Heterologous
two-photon spectroscopy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A carbon dot (C‐Dot)‐based two‐photon fluorescent probe has been developed for the monitoring of pH changes across a broad range with high sensitivity and selectivity. The inorganic–organic probe also shows good biocompatibility and cell permeability, and thus can be successfully applied in bioimaging and biosensing of physiological pH in living cells, as well as living tissues at a depth of 65–185 μm.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201202599