Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?

Abstract Schizophrenia spectrum and bipolar disorder are characterized by high levels of childhood trauma as well as of cognitive dysfunction. Our aim is to investigate the association between these two factors in the largest study in the literature so far. A total of 406 patients with schizophrenia...

Full description

Saved in:
Bibliographic Details
Published in:Psychiatry research 2012-08, Vol.198 (3), p.495-500
Main Authors: Aas, Monica, Steen, Nils E, Agartz, Ingrid, Aminoff, Sofie R, Lorentzen, Steinar, Sundet, Kjetil, Andreassen, Ole A, Melle, Ingrid
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Age Factors
Biological and medical sciences
Bipolar Disorder - complications
Bipolar Disorder - psychology
Bipolar disorders
Child
Childhood trauma
Cognition Disorders - complications
Cognition Disorders - psychology
Cognitive function
Executive Function
Female
Humans
Male
Medical sciences
Memory, Short-Term
Mood disorders
Neuropsychological Tests - statistics & numerical data
Other psychotic disorders
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychosis
Schizophrenia - complications
Schizophrenic Psychology
Stress, Psychological - complications
Stress, Psychological - psychology
Victimology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Schizophrenia spectrum and bipolar disorder are characterized by high levels of childhood trauma as well as of cognitive dysfunction. Our aim is to investigate the association between these two factors in the largest study in the literature so far. A total of 406 patients with schizophrenia spectrum- or bipolar disorders were recruited from a catchment area based organization in Oslo, Norway. Information about early life stress was obtained using the Childhood Trauma Questionnaire (CTQ). Cognitive function was assessed through a comprehensive and standardized neuropsychological test battery. Physical abuse, sexual abuse and physical neglect were significantly associated with reduced scores on working memory and executive function scales ( p = 0.04 to p < 0.001), and verbal and performance tasks from the Wechsler Abbreviated Scale of Intelligence ( WASI) ( p = 0.059 to p
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2011.12.045