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Nonlinear indices of circadian changes in individuals with dementia and aggression

Abstract Nonlinear analyses of actigraphy data were utilized to investigate circadian rest-activity system motor control in nursing-home residents with dementia and with/without aggressive behavior (AB). Significant differences observed between groups in measures of approximate entropy (ApEn) and fr...

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Bibliographic Details
Published in:Psychiatry research 2012-08, Vol.199 (1), p.77-78
Main Authors: Etcher, LuAnn, Whall, Ann, Kumar, Rahul, Devanand, Davangere, Yeragani, Vikram
Format: Article
Language:English
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Summary:Abstract Nonlinear analyses of actigraphy data were utilized to investigate circadian rest-activity system motor control in nursing-home residents with dementia and with/without aggressive behavior (AB). Significant differences observed between groups in measures of approximate entropy (ApEn) and fractal dimension (FD). ApEn and FD are sensitive to detecting and characterizing discrete changes in central motoric control and temporality of behaviors in dementia. Findings may inform understanding of clinical heterogeneity and possible physiologic sub-classifications of Alzheimer’s dementia.
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2012.03.042