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Safety and Efficacy of Fast-track Surgery in Laparoscopic Distal Gastrectomy for Gastric Cancer: A Randomized Clinical Trial

Background Fast-track surgery has been shown to enhance postoperative recovery in several surgical fields. This study aimed to evaluate the safety and efficacy of fast-track surgery in laparoscopic distal gastrectomy. Methods The present study was designed as a single-center, randomized, unblinded,...

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Bibliographic Details
Published in:World journal of surgery 2012-12, Vol.36 (12), p.2879-2887
Main Authors: Kim, Jong Won, Kim, Whan Sik, Cheong, Jae-Ho, Hyung, Woo Jin, Choi, Seung-Ho, Noh, Sung Hoon
Format: Article
Language:English
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Summary:Background Fast-track surgery has been shown to enhance postoperative recovery in several surgical fields. This study aimed to evaluate the safety and efficacy of fast-track surgery in laparoscopic distal gastrectomy. Methods The present study was designed as a single-center, randomized, unblinded, parallel-group trial. Patients were eligible if they had gastric cancer for which laparoscopic distal gastrectomy was indicated. The fast-track surgery protocol included intensive preoperative education, a short duration of fasting, a preoperative carbohydrate load, early postoperative ambulation, early feeding, and sufficient pain control using local anesthetics perfused via a local anesthesia pump device, with limited use of opioids. The primary endpoint was the duration of possible and actual postoperative hospital stay. Results We randomized 47 patients into a fast-track group ( n  = 22) and a conventional pathway group ( n  = 22), with three patients withdrawn. The possible and actual postoperative hospital stays were shorter in the fast-track group than in the conventional group (4.68 ± 0.65 vs. 7.05 ± 0.65; P  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-012-1741-7