Loading…
Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients
Background Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR). Objective We retrospectively analyzed the cost of dermatologic care in our OTR specialty clinic. Methods We collected billing data for OTR (n = 198) seen at the Dermatology Department of Zurich...
Saved in:
| Published in: | Journal of the American Academy of Dermatology 2012-12, Vol.67 (6), p.1242-1249 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043 |
| container_end_page | 1249 |
| container_issue | 6 |
| container_start_page | 1242 |
| container_title | Journal of the American Academy of Dermatology |
| container_volume | 67 |
| creator | Rüegg, Christian P Graf, Nicole, PhD Mühleisen, Beda, MD Szucs, Thomas D., MD French, Lars E., MD Surber, Christian, PhD Hofbauer, Günther F.L., MD |
| description | Background Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR). Objective We retrospectively analyzed the cost of dermatologic care in our OTR specialty clinic. Methods We collected billing data for OTR (n = 198) seen at the Dermatology Department of Zurich University Hospital over 4 years (2004-2007). Grouping by histology yielded the groups: SCC (n = 70), with SCC occurring within the observation period; past SCC (n = 40), with SCC before the observation period; in situ SCC (n = 13), when only in situ SCC had been diagnosed; biopsy negative (n = 49) for SCC and in situ SCC; and no biopsy ever (n = 26) within the observation period. Results Median annual costs for dermatologic care were US$1398 for SCC; US$776 for past SCC; US$308 for in situ SCC; US$211 for biopsy negative; and US$156 for no biopsy ever. Median cost per case of invasive SCC (US$1830) was higher than cost per case of in situ SCC (US$603). Regression analysis showed male sex ( P = .006), age at transplantation ( P = .001), and time since transplantation ( P |
| doi_str_mv | 10.1016/j.jaad.2012.03.033 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1178678936</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0190962212004811</els_id><sourcerecordid>1178678936</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043</originalsourceid><addsrcrecordid>eNp9kk2LFDEQhoMo7uzqH_AgfRG89Jgvkw6IsCy6CgseVs8hk1RrenvSs6luYf-91cyo4EEIBJLnraQeirEXgm8FF-bNsB1CSFvJhdxyRUs9YhvBnW2N7exjtuHC8dYZKc_YOeLAOXda2afsTErj3lKNDSu390vYTws2EcaxiaHGXKZ9aKa-mX9Ag3e5NLmkJQIhU8GcoIbdSDcLziEXSHSM88pTGIhtpvo9lGauoeBhDGVuKsR8yFBmfMae9GFEeH7aL9i3jx--Xn1qb75cf766vGmjtnpueyMdpNT1yslojRYCul4opY3W0sbIuXY2BuOSMjZB3AljnDKd1RRJXKsL9vpY91Cn-wVw9vuMa4ehADXrhbAdSaIMofKIxjohVuj9oeZ9qA9ecL969oNfPfvVs-eKlqLQy1P9ZbeH9CfyWywBr05AwBjGnmTEjH85Y6yTci307sgB2fiZoXqMZCpCymRt9mnK___H-3_iccwl04t38AA4TEst5NkLj5Txt-tErAMhJCnshFC_APv5sKA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1178678936</pqid></control><display><type>article</type><title>Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients</title><source>Elsevier:Jisc Collections:Elsevier Read and Publish Agreement 2022-2024:Freedom Collection (Reading list)</source><creator>Rüegg, Christian P ; Graf, Nicole, PhD ; Mühleisen, Beda, MD ; Szucs, Thomas D., MD ; French, Lars E., MD ; Surber, Christian, PhD ; Hofbauer, Günther F.L., MD</creator><creatorcontrib>Rüegg, Christian P ; Graf, Nicole, PhD ; Mühleisen, Beda, MD ; Szucs, Thomas D., MD ; French, Lars E., MD ; Surber, Christian, PhD ; Hofbauer, Günther F.L., MD</creatorcontrib><description>Background Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR). Objective We retrospectively analyzed the cost of dermatologic care in our OTR specialty clinic. Methods We collected billing data for OTR (n = 198) seen at the Dermatology Department of Zurich University Hospital over 4 years (2004-2007). Grouping by histology yielded the groups: SCC (n = 70), with SCC occurring within the observation period; past SCC (n = 40), with SCC before the observation period; in situ SCC (n = 13), when only in situ SCC had been diagnosed; biopsy negative (n = 49) for SCC and in situ SCC; and no biopsy ever (n = 26) within the observation period. Results Median annual costs for dermatologic care were US$1398 for SCC; US$776 for past SCC; US$308 for in situ SCC; US$211 for biopsy negative; and US$156 for no biopsy ever. Median cost per case of invasive SCC (US$1830) was higher than cost per case of in situ SCC (US$603). Regression analysis showed male sex ( P = .006), age at transplantation ( P = .001), and time since transplantation ( P < .001) as independent cost factors. Limitations This was an open, retrospective, single-center study with limited patient numbers. Conclusion Dermatologic care for OTR is costly, and the majority of the costs are associated with SCC. Once SCC occurs, costs increase in a pronounced and sustained fashion. Interventions reducing the progression from in situ SCC to SCC could lead to considerable financial savings. We advocate sun protection, early diagnosis, and intervention to minimize the costs associated with SCC.</description><identifier>ISSN: 0190-9622</identifier><identifier>EISSN: 1097-6787</identifier><identifier>DOI: 10.1016/j.jaad.2012.03.033</identifier><identifier>PMID: 22695101</identifier><identifier>CODEN: JAADDB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Biological and medical sciences ; Carcinoma, Squamous Cell - economics ; Carcinoma, Squamous Cell - therapy ; cost of care ; Dermatology ; Female ; Health Care Costs ; Humans ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; nonmelanoma skin cancer ; organ transplant recipients ; Organ Transplantation ; Postoperative Complications - economics ; Postoperative Complications - therapy ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Retrospective Studies ; Skin Neoplasms - economics ; Skin Neoplasms - therapy ; squamous cell carcinoma ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Journal of the American Academy of Dermatology, 2012-12, Vol.67 (6), p.1242-1249</ispartof><rights>American Academy of Dermatology, Inc.</rights><rights>2012 American Academy of Dermatology, Inc.</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043</citedby><cites>FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26679223$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22695101$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rüegg, Christian P</creatorcontrib><creatorcontrib>Graf, Nicole, PhD</creatorcontrib><creatorcontrib>Mühleisen, Beda, MD</creatorcontrib><creatorcontrib>Szucs, Thomas D., MD</creatorcontrib><creatorcontrib>French, Lars E., MD</creatorcontrib><creatorcontrib>Surber, Christian, PhD</creatorcontrib><creatorcontrib>Hofbauer, Günther F.L., MD</creatorcontrib><title>Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients</title><title>Journal of the American Academy of Dermatology</title><addtitle>J Am Acad Dermatol</addtitle><description>Background Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR). Objective We retrospectively analyzed the cost of dermatologic care in our OTR specialty clinic. Methods We collected billing data for OTR (n = 198) seen at the Dermatology Department of Zurich University Hospital over 4 years (2004-2007). Grouping by histology yielded the groups: SCC (n = 70), with SCC occurring within the observation period; past SCC (n = 40), with SCC before the observation period; in situ SCC (n = 13), when only in situ SCC had been diagnosed; biopsy negative (n = 49) for SCC and in situ SCC; and no biopsy ever (n = 26) within the observation period. Results Median annual costs for dermatologic care were US$1398 for SCC; US$776 for past SCC; US$308 for in situ SCC; US$211 for biopsy negative; and US$156 for no biopsy ever. Median cost per case of invasive SCC (US$1830) was higher than cost per case of in situ SCC (US$603). Regression analysis showed male sex ( P = .006), age at transplantation ( P = .001), and time since transplantation ( P < .001) as independent cost factors. Limitations This was an open, retrospective, single-center study with limited patient numbers. Conclusion Dermatologic care for OTR is costly, and the majority of the costs are associated with SCC. Once SCC occurs, costs increase in a pronounced and sustained fashion. Interventions reducing the progression from in situ SCC to SCC could lead to considerable financial savings. We advocate sun protection, early diagnosis, and intervention to minimize the costs associated with SCC.</description><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - economics</subject><subject>Carcinoma, Squamous Cell - therapy</subject><subject>cost of care</subject><subject>Dermatology</subject><subject>Female</subject><subject>Health Care Costs</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>nonmelanoma skin cancer</subject><subject>organ transplant recipients</subject><subject>Organ Transplantation</subject><subject>Postoperative Complications - economics</subject><subject>Postoperative Complications - therapy</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Retrospective Studies</subject><subject>Skin Neoplasms - economics</subject><subject>Skin Neoplasms - therapy</subject><subject>squamous cell carcinoma</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kk2LFDEQhoMo7uzqH_AgfRG89Jgvkw6IsCy6CgseVs8hk1RrenvSs6luYf-91cyo4EEIBJLnraQeirEXgm8FF-bNsB1CSFvJhdxyRUs9YhvBnW2N7exjtuHC8dYZKc_YOeLAOXda2afsTErj3lKNDSu390vYTws2EcaxiaHGXKZ9aKa-mX9Ag3e5NLmkJQIhU8GcoIbdSDcLziEXSHSM88pTGIhtpvo9lGauoeBhDGVuKsR8yFBmfMae9GFEeH7aL9i3jx--Xn1qb75cf766vGmjtnpueyMdpNT1yslojRYCul4opY3W0sbIuXY2BuOSMjZB3AljnDKd1RRJXKsL9vpY91Cn-wVw9vuMa4ehADXrhbAdSaIMofKIxjohVuj9oeZ9qA9ecL969oNfPfvVs-eKlqLQy1P9ZbeH9CfyWywBr05AwBjGnmTEjH85Y6yTci307sgB2fiZoXqMZCpCymRt9mnK___H-3_iccwl04t38AA4TEst5NkLj5Txt-tErAMhJCnshFC_APv5sKA</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Rüegg, Christian P</creator><creator>Graf, Nicole, PhD</creator><creator>Mühleisen, Beda, MD</creator><creator>Szucs, Thomas D., MD</creator><creator>French, Lars E., MD</creator><creator>Surber, Christian, PhD</creator><creator>Hofbauer, Günther F.L., MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients</title><author>Rüegg, Christian P ; Graf, Nicole, PhD ; Mühleisen, Beda, MD ; Szucs, Thomas D., MD ; French, Lars E., MD ; Surber, Christian, PhD ; Hofbauer, Günther F.L., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - economics</topic><topic>Carcinoma, Squamous Cell - therapy</topic><topic>cost of care</topic><topic>Dermatology</topic><topic>Female</topic><topic>Health Care Costs</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>nonmelanoma skin cancer</topic><topic>organ transplant recipients</topic><topic>Organ Transplantation</topic><topic>Postoperative Complications - economics</topic><topic>Postoperative Complications - therapy</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Retrospective Studies</topic><topic>Skin Neoplasms - economics</topic><topic>Skin Neoplasms - therapy</topic><topic>squamous cell carcinoma</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rüegg, Christian P</creatorcontrib><creatorcontrib>Graf, Nicole, PhD</creatorcontrib><creatorcontrib>Mühleisen, Beda, MD</creatorcontrib><creatorcontrib>Szucs, Thomas D., MD</creatorcontrib><creatorcontrib>French, Lars E., MD</creatorcontrib><creatorcontrib>Surber, Christian, PhD</creatorcontrib><creatorcontrib>Hofbauer, Günther F.L., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rüegg, Christian P</au><au>Graf, Nicole, PhD</au><au>Mühleisen, Beda, MD</au><au>Szucs, Thomas D., MD</au><au>French, Lars E., MD</au><au>Surber, Christian, PhD</au><au>Hofbauer, Günther F.L., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>67</volume><issue>6</issue><spage>1242</spage><epage>1249</epage><pages>1242-1249</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Background Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR). Objective We retrospectively analyzed the cost of dermatologic care in our OTR specialty clinic. Methods We collected billing data for OTR (n = 198) seen at the Dermatology Department of Zurich University Hospital over 4 years (2004-2007). Grouping by histology yielded the groups: SCC (n = 70), with SCC occurring within the observation period; past SCC (n = 40), with SCC before the observation period; in situ SCC (n = 13), when only in situ SCC had been diagnosed; biopsy negative (n = 49) for SCC and in situ SCC; and no biopsy ever (n = 26) within the observation period. Results Median annual costs for dermatologic care were US$1398 for SCC; US$776 for past SCC; US$308 for in situ SCC; US$211 for biopsy negative; and US$156 for no biopsy ever. Median cost per case of invasive SCC (US$1830) was higher than cost per case of in situ SCC (US$603). Regression analysis showed male sex ( P = .006), age at transplantation ( P = .001), and time since transplantation ( P < .001) as independent cost factors. Limitations This was an open, retrospective, single-center study with limited patient numbers. Conclusion Dermatologic care for OTR is costly, and the majority of the costs are associated with SCC. Once SCC occurs, costs increase in a pronounced and sustained fashion. Interventions reducing the progression from in situ SCC to SCC could lead to considerable financial savings. We advocate sun protection, early diagnosis, and intervention to minimize the costs associated with SCC.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>22695101</pmid><doi>10.1016/j.jaad.2012.03.033</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0190-9622 |
| ispartof | Journal of the American Academy of Dermatology, 2012-12, Vol.67 (6), p.1242-1249 |
| issn | 0190-9622 1097-6787 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1178678936 |
| source | Elsevier:Jisc Collections:Elsevier Read and Publish Agreement 2022-2024:Freedom Collection (Reading list) |
| subjects | Biological and medical sciences Carcinoma, Squamous Cell - economics Carcinoma, Squamous Cell - therapy cost of care Dermatology Female Health Care Costs Humans Male Medical sciences Middle Aged Miscellaneous nonmelanoma skin cancer organ transplant recipients Organ Transplantation Postoperative Complications - economics Postoperative Complications - therapy Public health. Hygiene Public health. Hygiene-occupational medicine Retrospective Studies Skin Neoplasms - economics Skin Neoplasms - therapy squamous cell carcinoma Tumors of the skin and soft tissue. Premalignant lesions |
| title | Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T16%3A58%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Squamous%20cell%20carcinoma%20of%20the%20skin%20induces%20considerable%20sustained%20cost%20of%20care%20in%20organ%20transplant%20recipients&rft.jtitle=Journal%20of%20the%20American%20Academy%20of%20Dermatology&rft.au=R%C3%BCegg,%20Christian%20P&rft.date=2012-12-01&rft.volume=67&rft.issue=6&rft.spage=1242&rft.epage=1249&rft.pages=1242-1249&rft.issn=0190-9622&rft.eissn=1097-6787&rft.coden=JAADDB&rft_id=info:doi/10.1016/j.jaad.2012.03.033&rft_dat=%3Cproquest_cross%3E1178678936%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c474t-f629edd8f392c76411e8f133464427cc00497ca69d367decb1669368748f3d043%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1178678936&rft_id=info:pmid/22695101&rfr_iscdi=true |