Torus mandibularis bone chips combined with platelet rich plasma gel for treatment of intrabony osseous defects: clinical and radiographic evaluation

Abstract The use of platelet rich plasma (PRP) gel in combination with torus mandibularis offers a potentially useful treatment for periodontal osseous defects. Whether this combination enhances the outcome of periodontal regenerative therapy is not known. This study compared the effectiveness of to...

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Bibliographic Details
Published in:International journal of oral and maxillofacial surgery 2012-12, Vol.41 (12), p.1519-1526
Main Authors: Hassan, K.S, Alagl, A.S, Abdel-Hady, A
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Dentistry
Double-Blind Method
Exostoses
Female
Gels
Humans
intrabony osseous defects
Male
Mandible - abnormalities
Mandibular Diseases - diagnostic imaging
Mandibular Diseases - therapy
Medical sciences
Otorhinolaryngology. Stomatology
Palate, Hard - abnormalities
Platelet-Rich Plasma
Radiography
Surgery
torus mandibularis
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Summary:Abstract The use of platelet rich plasma (PRP) gel in combination with torus mandibularis offers a potentially useful treatment for periodontal osseous defects. Whether this combination enhances the outcome of periodontal regenerative therapy is not known. This study compared the effectiveness of torus mandibularis bone chips alone and when combined with autogenous PRP gel in treating periodontal osseous defects. 24 sites from 12 patients were selected using a split mouth design and determined by a double-blind, randomized, controlled clinical trial. Both sites received a full-thickness mucoperiosteal flap; one intrabony defect was filled with torus mandibularis bone chips alone and the other with torus mandibularis bone chips mixed with PRP gel. There was a 57% gain in the clinical attachment level and 60% reduction in the probing depth for torus mandibularis alone compared to 72% and 68% for sites treated with torus mandibularis and PRP gel ( p ≤ 0.01). There was a statistically significant difference in the bone dentistry and the marginal bone loss at sites with PRP gel compared to those without gel ( p ≤ 0.01). The use of mandibular tori as autogenous bone graft combined with PRP gel showed a significant improvement in the clinical outcome of periodontal therapy than mandibular tori alone.
ISSN:0901-5027
1399-0020
DOI:10.1016/j.ijom.2012.02.009