Malignant amelanotic melanoma--a diagnostic surprise: Flurodeoxyglocose Positron Emission Tomography-Computed Tomography and immunohistochemistry clinch the 'final diagnosis'

Amelanotic melanoma is a rare malignancy and the prognosis is usually poorer than that of pigmented melanomas, because of delay in establishing the correct diagnosis, and in treatment initiation. In our case report, we present a the Flurodeoxyglocose Positron Emission Tomography-Computed Tomography...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2012-07, Vol.8 (3), p.451-453
Main Authors: Joshi, Prathamesh V, Lele, Vikram R, Aland, Nusrat J, Bhat, Ganapathi, Ajinkya, Snigdha Pratap, Patel, Roma P
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Care and treatment
Case studies
Diagnosis
Diagnosis, Differential
Fluorodeoxyglucose F18
Health aspects
Humans
Immunohistochemistry
Immunohistochemistry - methods
Liver Neoplasms - drug therapy
Liver Neoplasms - secondary
Male
Medical diagnosis
Melanoma
Melanoma, Amelanotic - diagnosis
Melanoma, Amelanotic - diagnostic imaging
Melanoma, Amelanotic - surgery
Middle Aged
Multimodal Imaging - methods
PET imaging
Positron-Emission Tomography
Radiopharmaceuticals
Skin - pathology
Skin Neoplasms - diagnosis
Skin Neoplasms - diagnostic imaging
Skin Neoplasms - surgery
Tomography
Tomography, X-Ray Computed
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Summary:Amelanotic melanoma is a rare malignancy and the prognosis is usually poorer than that of pigmented melanomas, because of delay in establishing the correct diagnosis, and in treatment initiation. In our case report, we present a the Flurodeoxyglocose Positron Emission Tomography-Computed Tomography (FDG PET/CT) findings of a patient suffering from malignant amelanotic melanoma and its histopathological confirmation and immunohistochemistry (IHC) correlation In the described case, amelanotic melanoma masqueraded as adenocarcinoma of the rectum in the pathology as well the clinical course. Our case highlights the importance of obtaining a tissue diagnosis and IHC confirmation whenever unusual PET/CT findings are encountered.
ISSN:0973-1482
1998-4138
DOI:10.4103/0973-1482.103533