Type 2 innate lymphoid cells: new players in asthma and allergy

Highlights ► ILC2 play a critical role in type 2 immunity. ► ILC2 proliferate during experimental asthma responses. ► IL-13 production by ILC2 contributes to allergic asthma.

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Bibliographic Details
Published in:Current opinion in immunology 2012-12, Vol.24 (6), p.707-712
Main Authors: Scanlon, Seth T, McKenzie, Andrew NJ
Format: Article
Language:English
Subjects:
Allergy and Immunology
Asthma - immunology
Humans
Hypersensitivity - immunology
Interleukin-13 - metabolism
Interleukin-5 - metabolism
Lymphocytes - physiology
Nuclear Receptor Subfamily 1, Group F, Member 1 - immunology
Th1 Cells - physiology
Th17 Cells - physiology
Th2 Cells - physiology
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Description
Summary:Highlights ► ILC2 play a critical role in type 2 immunity. ► ILC2 proliferate during experimental asthma responses. ► IL-13 production by ILC2 contributes to allergic asthma.
ISSN:0952-7915
1879-0372
DOI:10.1016/j.coi.2012.08.009