Autoimmune polyglandular syndrome: an unusual presentation with empty sella, premature ovarian failure, and Hashimoto's thyroiditis associated with thyroid cancer

Autoimmune polyglandular syndromes are rare disorders characterized by failure of several endocrine glands, as well as non-endocrine organs, associated with immune-mediated tissue destruction. We report a rare case of polyglandular syndrome type II in a patient who presented with premature ovarian f...

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Bibliographic Details
Published in:Gynecological endocrinology 2012-12, Vol.28 (12), p.999-1001
Main Authors: Leães, Carolina Garcia Soares, Rios, Maria Carolina, Passaglia, Juliana Pereira, Pereira-Lima, Julia Fernanda, Oliveira, Miriam da Costa
Format: Article
Language:English
Subjects:
Adult
Carcinoma - complications
Carcinoma - surgery
Empty Sella Syndrome - etiology
Female
Hashimoto Disease - etiology
Hormone Replacement Therapy
Humans
Polyendocrinopathies, Autoimmune - complications
Polyendocrinopathies, Autoimmune - drug therapy
Polyendocrinopathies, Autoimmune - physiopathology
Primary Ovarian Insufficiency - etiology
Thyroid Neoplasms - complications
Thyroid Neoplasms - surgery
Thyroidectomy - adverse effects
Treatment Outcome
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Summary:Autoimmune polyglandular syndromes are rare disorders characterized by failure of several endocrine glands, as well as non-endocrine organs, associated with immune-mediated tissue destruction. We report a rare case of polyglandular syndrome type II in a patient who presented with premature ovarian failure, Hashimoto's thyroiditis and empty sella associated with a diagnosis of differentiated thyroid carcinoma. This case probably represents the first report on this tumor in a patient with polyglandular disorder.
ISSN:0951-3590
1473-0766
DOI:10.3109/09513590.2012.692222