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Synthesis of allenamides by Pd-catalyzed coupling of 3-alkoxycarbonyloxy ynamides or 1-alkoxycarbonyloxy allenamides with arylboronic acids

An efficient palladium-catalyzed method is reported for the synthesis of multi-substituted allenamides by Suzuki-Miyaura cross-coupling reaction between easily prepared 3-alkoxycarbonyloxy ynamides or 1-alkoxycarbonyloxy allenamides and arylboronic acids.

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2012-01, Vol.10 (48), p.9556-9561
Main Authors: Cao, Jian, Kong, Yulong, Deng, Yuan, Lai, Guoqiao, Cui, Yuming, Hu, Ziqiang, Wang, Guanhai
Format: Article
Language:English
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Summary:An efficient palladium-catalyzed method is reported for the synthesis of multi-substituted allenamides by Suzuki-Miyaura cross-coupling reaction between easily prepared 3-alkoxycarbonyloxy ynamides or 1-alkoxycarbonyloxy allenamides and arylboronic acids.
ISSN:1477-0520
1477-0539
DOI:10.1039/c2ob26727f