Phenotypic and allelic profile of ABO and Rhésus D blood group system among blood donor in Antananarivo

Summary This study assessed the phenotypic and allelic profiles of ABO and Rhesus D blood group system among first time blood donors at the National Centre of Blood Supply of Antananarivo. We collected through this retrospective study all data registered during 7 years of practice (from 2003 to 2009...

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Bibliographic Details
Published in:International journal of immunogenetics 2012-12, Vol.39 (6), p.477-479
Main Authors: Randriamanantany, Z. A., Rajaonatahina, D. H., Razafimanantsoa, F. E., Rasamindrakotroka, M. T., Andriamahenina, R., Rasoarilalamanarivo, F. B., Hanitriniala, S. P., Herisoa, F. R., Rasamindrakotroka, A., Rakoto Alson, O. A.
Format: Article
Language:English
Subjects:
ABO Blood-Group System - genetics
ABO system
Adult
Age
Alleles
Blood Donors
Blood groups
Data processing
Female
Gene frequency
Humans
Madagascar
Male
Monoclonal antibodies
O antigen
Phenotype
Rh-Hr Blood-Group System - genetics
Sex
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Summary:Summary This study assessed the phenotypic and allelic profiles of ABO and Rhesus D blood group system among first time blood donors at the National Centre of Blood Supply of Antananarivo. We collected through this retrospective study all data registered during 7 years of practice (from 2003 to 2009). Age and sex were analysed with the result of ABO and RhD screening. They were tested both with Beth Vincent and Simonin tests which were performed in a plate, by using commercial monoclonal antibody (Diaclone® et Eryclone®), and home‐made red cells tests. The Rh D was performed with the same commercial kits. The frequencies of alleles were calculated by using Bernstein method. Data about 45 857 donors were obtained. A male predominance (80.46%) was found and most of our donors were aged
ISSN:1744-3121
1744-313X
DOI:10.1111/j.1744-313X.2012.01120.x