Thyrocyte calcium response to changes in thyroid function

Calcium regulation in thyrocytes of rats with thyroid hyper- and hypofunction is studied. A single, but not prolonged, administration of thyrotropin increases the cytoplasmic calcium content. A course of triiodothyronine injections increases calcium level and suppresses the thyroid hormone function....

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1998-01, Vol.125 (1), p.87-89
Main Authors: Stroev, E. A., Bulaeva, N. N., Kochukov, M. Yu, Nikolaev, V. V.
Format: Article
Language:English
Subjects:
ATP
Calcium
Carbachol
Glands
thyrocytes
Thyroid gland
Thyroid hormones
Thyroid-stimulating hormone
Triiodothyronine
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Summary:Calcium regulation in thyrocytes of rats with thyroid hyper- and hypofunction is studied. A single, but not prolonged, administration of thyrotropin increases the cytoplasmic calcium content. A course of triiodothyronine injections increases calcium level and suppresses the thyroid hormone function. Study ofin vitro calcium response of thyrocytes revealed decreased sensitivity of these cells to carbacholine, thyrotropin, and ATP and decreased functional activity of the gland.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02496810