Tributyl Borate Mediated Biginelli Reaction: A Facile Microwave-Assisted Green Synthetic Strategy toward Dihydropyrimidinones

Exploitation of a new boron-based catalyst, tributyl borate, for the formation of dihydropyrimidinones under solvent-free microwave-assisted conditions is described. The method is a simple, easy, fast, cost effective, and potentially green protocol for the formation of multi-functionalized pharmacol...

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Bibliographic Details
Published in:Bulletin of the Chemical Society of Japan 2010-03, Vol.83 (3), p.288-290
Main Authors: Ranjith, Choorikkat, Srinivasan, G. V, Vijayan, K. K
Format: Article
Language:English
Subjects:
Borates
Catalysts
Exploitation
Strategy
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Summary:Exploitation of a new boron-based catalyst, tributyl borate, for the formation of dihydropyrimidinones under solvent-free microwave-assisted conditions is described. The method is a simple, easy, fast, cost effective, and potentially green protocol for the formation of multi-functionalized pharmacologically active dihydropyrimidinones.
ISSN:0009-2673
1348-0634
1348-0634
DOI:10.1246/bcsj.20090275