Modeling Transcriptome Dynamics in a Complex World

An accurate prediction of how extrinsic stimuli influence changes in gene expression has been challenging. In this issue, Nagano and colleagues successfully model genome-wide mRNA expression changes under variable environmental conditions in rice, raising hopes that scientists will soon be able to p...

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Bibliographic Details
Published in:Cell 2012-12, Vol.151 (6), p.1161-1162
Main Authors: Jaeger, Philipp A., Doherty, Colleen, Ideker, Trey
Format: Article
Language:English
Subjects:
environmental factors
gene expression
gene expression regulation
messenger RNA
prediction
rice
scientists
transcription (genetics)
transcriptome
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Summary:An accurate prediction of how extrinsic stimuli influence changes in gene expression has been challenging. In this issue, Nagano and colleagues successfully model genome-wide mRNA expression changes under variable environmental conditions in rice, raising hopes that scientists will soon be able to predict genome-wide transcriptional responses in a variety of organisms in uncontrolled real-world settings.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2012.11.031