HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women

Abstract We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load ( r2 = − 0.8900, P < 0.01), which may have implications of increased chance...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2013, Vol.75 (1), p.112-114
Main Authors: Mane, Arati, Kulkarni, Smita, Ghate, Manisha, Risbud, Arun, Thakar, Madhuri
Format: Article
Language:English
Subjects:
Adult
Asymptomatic Diseases
Bacterial Load
Cross-Sectional Studies
Female
Genital shedding
HIV Infections - virology
HIV-1
HIV-1 - genetics
Humans
Infectious Disease
Internal Medicine
Lactobacilli
Lactobacillus - isolation & purification
RNA, Viral - isolation & purification
Vagina - microbiology
Virus Shedding
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load ( r2 = − 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2012.09.009