Incidence of Cleft Lip and Palate in Gorgan - Northern Iran: An Epidemiological Study

Cleft lip with or without cleft palate is the most common orofacial congenital anomaly among live births. This study was carried out to determine the incidence rate of oral clefting in Gorgan, Northern Iran during 2004-2009. This descriptive hospital-based study was performed on 35,009 live newborns...

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Published in:Oman medical journal 2012-11, Vol.27 (6), p.461-464
Main Authors: Hosseinpour , Kaniz Reza, Kaviany , Nafiseh, Mirfazeli , Arezou
Format: Article
Language:English
Subjects:
CHILDREN
Cleft lip
Cleft palate
DISTORTION
Ethnicity
Gender
HEREDITARY DISEASES
IRAN
IRAQ
MOUTH
OBSTETRICS
Original
PALATE
إيران
الأطفال
الأمراض الوراثية
التشوهات الخلقية
الحنك
العراق
الفم
طب التوليد
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Kaviany , Nafiseh
Mirfazeli , Arezou
description Cleft lip with or without cleft palate is the most common orofacial congenital anomaly among live births. This study was carried out to determine the incidence rate of oral clefting in Gorgan, Northern Iran during 2004-2009. This descriptive hospital-based study was performed on 35,009 live newborns in Dezyani Hospital in Gorgan, Northern Iran during 2004-2009. All newborns were screened for oral clefts. Data including birth date, gender, type of oral clefts, parents' consanguinity, parental ethnicity and presence of other congenital anomalies were recorded for analysis. The overall incidence rate of oral clefts during this 6-year period was 1.05 per 1000, or 1 per 946 live births. The incidence of cleft lip and isolated cleft palate was 0.08 and 0.37 per 1,000 live births, respectively. The ratio for different cleft types was 1:7:4 (CL: CLP: CP). The incidence of oral clefting was 1.2 per 1,000 male births and 0.86 per 1,000 female births (RR=1.40; 95% CI: 0.73-2.71). According to parental ethnicity, the incidence of oral clefting was 0.7, 1.7 and 1.26 per 1,000 in Native Fars, Turkman and Sistani, respectively. The relative risk for oral clefting in Turkman to native Fars group was 2.56 (p
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This study was carried out to determine the incidence rate of oral clefting in Gorgan, Northern Iran during 2004-2009. This descriptive hospital-based study was performed on 35,009 live newborns in Dezyani Hospital in Gorgan, Northern Iran during 2004-2009. All newborns were screened for oral clefts. Data including birth date, gender, type of oral clefts, parents' consanguinity, parental ethnicity and presence of other congenital anomalies were recorded for analysis. The overall incidence rate of oral clefts during this 6-year period was 1.05 per 1000, or 1 per 946 live births. The incidence of cleft lip and isolated cleft palate was 0.08 and 0.37 per 1,000 live births, respectively. The ratio for different cleft types was 1:7:4 (CL: CLP: CP). The incidence of oral clefting was 1.2 per 1,000 male births and 0.86 per 1,000 female births (RR=1.40; 95% CI: 0.73-2.71). According to parental ethnicity, the incidence of oral clefting was 0.7, 1.7 and 1.26 per 1,000 in Native Fars, Turkman and Sistani, respectively. The relative risk for oral clefting in Turkman to native Fars group was 2.56 (p&lt;0.02). In this study, 56.7% of clefts were CL+P, 8.1% were CL and 35.1% of cases were CP. CP was more common among girls (54%) than among boys (46%) but CL was more common among boys. 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subjects CHILDREN
Cleft lip
Cleft palate
DISTORTION
Ethnicity
Gender
HEREDITARY DISEASES
IRAN
IRAQ
MOUTH
OBSTETRICS
Original
PALATE
إيران
الأطفال
الأمراض الوراثية
التشوهات الخلقية
الحنك
العراق
الفم
طب التوليد
title Incidence of Cleft Lip and Palate in Gorgan - Northern Iran: An Epidemiological Study
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