Quantitative analysis of brain synaptophysin (p38) in offspring of male rats with chronic morphine intoxication

Cerebral synapses in offspring of male rats treated with morphine for a month before mating were studied using synaptophysin (p38) as a synaptic marker. The content of p38 in the nucleus accumbens, hippocampus, and layers III and V of the somatosensory cortex was below the control, while no signific...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2000-01, Vol.129 (1), p.41-43
Main Authors: Khrenov, A. I., Belichenko, P. V., Shamakina, I. Yu
Format: Article
Language:English
Subjects:
Brain
Rodents
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Summary:Cerebral synapses in offspring of male rats treated with morphine for a month before mating were studied using synaptophysin (p38) as a synaptic marker. The content of p38 in the nucleus accumbens, hippocampus, and layers III and V of the somatosensory cortex was below the control, while no significant changes were found in the motor cortex, caudate nucleus, and ventrolateral thalamic nuclei.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433864