Benzamide and its derivatives are active against botulinal intoxication

A high antibotulinal activity of benzamide injected for prevention and of 3-N-butyrylamino-benzamide injected for treatment was observed in mice with intoxication caused by type A botulin toxin. 3-aminobenzamide and 3-N-butyrylaminobenzamide did not inhibit botulinal toxinin vitro.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1997-06, Vol.123 (6), p.593-595
Main Authors: Ugryumova, G. A., Krasil'nikov, I. I., Alferova, O. F., Vinogradova, I. D., Vertiev, Yu. V.
Format: Article
Language:English
Subjects:
Intoxication
Toxins
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Summary:A high antibotulinal activity of benzamide injected for prevention and of 3-N-butyrylamino-benzamide injected for treatment was observed in mice with intoxication caused by type A botulin toxin. 3-aminobenzamide and 3-N-butyrylaminobenzamide did not inhibit botulinal toxinin vitro.
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02458088