Photoacoustic and ultrasound dual-modality imaging of human peripheral joints

A photoacoustic (PA) and ultrasound (US) dual modality system, for imaging human peripheral joints, is introduced. The system utilizes a commercial US unit for both US control imaging and PA signal acquisition. Preliminary in vivo evaluation of the system, on normal volunteers, revealed that this sy...

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Bibliographic Details
Published in:Journal of biomedical optics 2013-01, Vol.18 (1), p.010502-010502
Main Authors: Xu, Guan, Rajian, Justin R, Girish, Gandikota, Kaplan, Mariana J, Fowlkes, J. Brian, Carson, Paul L, Wang, Xueding
Format: Article
Language:English
Subjects:
Algorithms
Female
Finger Joint - diagnostic imaging
Humans
Image Processing, Computer-Assisted - methods
JBO Letters
Male
Photoacoustic Techniques - methods
Ultrasonography - methods
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Description
Summary:A photoacoustic (PA) and ultrasound (US) dual modality system, for imaging human peripheral joints, is introduced. The system utilizes a commercial US unit for both US control imaging and PA signal acquisition. Preliminary in vivo evaluation of the system, on normal volunteers, revealed that this system can recover both the structural and functional information of intra- and extra-articular tissues. Confirmed by the control US images, the system, on the PA mode, can differentiate tendon from surrounding soft tissue based on the endogenous optical contrast. Presenting both morphological and pathological information in joint, this system holds promise for diagnosis and characterization of inflammatory joint diseases such as rheumatoid arthritis.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.18.1.010502