Subpopulation of Colorectal Adenocarcinoma Cells Co-Expressing CD133 and Cancer Stem Cells Markers of Other Tumors

Co-expression of colorectal adenocarcinoma cancer stem cells marker CD133 and a set of surface molecules described in published reports as possible cancer stem cell markers of other solid tumors was analyzed by fl ow cytometry. Minor cell populations expressing CD29, CD34, CD90, and CD117 against th...

Full description

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2012-04, Vol.152 (6), p.739-742
Main Authors: Gisina, A. M., Lupatov, A. Yu, Karalkin, P. A., Mainovskaya, O. A., Petrov, L. O., Sidorov, D. V., Frank, G. A., Yarygin, K. N.
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenocarcinoma - genetics
Adenocarcinoma - immunology
Adenocarcinoma - pathology
Antigens, CD - genetics
Antigens, CD - immunology
Biomarkers, Tumor - genetics
Biomarkers, Tumor - immunology
Biomedical and Life Sciences
Biomedicine
Biopsy
CD29 antigen
CD34 antigen
CD90 antigen
Cell Biology
Cell suspensions
Colorectal cancer
Colorectal Neoplasms - genetics
Colorectal Neoplasms - immunology
Colorectal Neoplasms - pathology
Cytometry
Flow Cytometry
Gene Expression
Humans
Internal Medicine
Laboratory Medicine
Leukemia
Neoplastic Stem Cells - immunology
Neoplastic Stem Cells - metabolism
Neoplastic Stem Cells - pathology
Oncology
Pathology
Solid tumors
Stem cells
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Co-expression of colorectal adenocarcinoma cancer stem cells marker CD133 and a set of surface molecules described in published reports as possible cancer stem cell markers of other solid tumors was analyzed by fl ow cytometry. Minor cell populations expressing CD29, CD34, CD90, and CD117 against the background of CD133 expression were detected in cancer cells suspensions from the patients with colorectal adenocarcinoma. Our fi ndings suggest that these markers can be used as additional markers of cancer stem cells of human colorectal adenocarcinoma.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-012-1620-0