Changes in morphology, cytoskeleton, and substrate dependence of proliferation after transfection of immortalized rat embryonic fibroblasts with E7 gene of type 16 human papilloma virus

Transfection of rat embryonic fibroblasts with E7 gene of type 16 human papilloma virus changed the cytoskeleton and cell-cell and cell-matrix interactions in two clones of transformed cells. Cell morphology and substrate-dependent proliferation were also changed.[PUBLICATION ABSTRACT]

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1999-01, Vol.127 (1), p.99-102
Main Authors: Zhurbitskaya, V. A., Rovenskii, Yu. A., Kaverina, I. N.
Format: Article
Language:English
Subjects:
Cytology
Cytoskeleton
Dependence
double prime E7 gene
Embryo fibroblasts
Transfection
Transformed cells
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Description
Summary:Transfection of rat embryonic fibroblasts with E7 gene of type 16 human papilloma virus changed the cytoskeleton and cell-cell and cell-matrix interactions in two clones of transformed cells. Cell morphology and substrate-dependent proliferation were also changed.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02432813