Determination of optical properties of tissues

• Published in: Journal of quantitative spectroscopy & radiative transfer 2011-09, Vol.112 (13), p.2128-2133
• Main Authors: Chaikovskaya, L.I., Tsarjuk, O.V., Belotserkovsky, I.V., Vozmitel, M.A.
• Format: Article
• Language: English
• Subjects: Analytical approximation; Extinction; Lasers; Light propagation in tissues; Mathematical analysis; Optical constants measurement; Optical diagnostics for medicine; Optical properties; Radiative transfer; Radiative transfer theory; Spectroscopy; Tissue optical properties; Tumors; Wavelengths
• ISSN: 0022-4073; 1879-1352
• DOI: 10.1016/j.jqsrt.2011.02.012

Recent results and used way of tissue optical properties measurements in vitro with laser goniophotometer are presented. The optical properties were obtained on the basis of an indirect technique using solution of the radiative transfer equation, which relate the optical parameters of tissue with the measured parameters of reflected and transmitted radiation. The angular patterns of reflected and transmitted radiation by optically thick saline-soaked samples of tumor tissue, namely, mammary fibroadenoma, were measured at the wavelength of 0.63 μm, and the measurement data were inverted to find the absorption and extinction coefficients and the parameters of the phase function of these tumor samples. Obtained values of the optical parameters have been found to be of the same order of magnitude as the earlier reported data for similar tumor samples. ► We develop technique to find optical properties of tissue from goniophotometric measurements. ► We create iterative procedure for inversion of data obtained on thick tissue samples. ► Absorption, extinction and phase function of tissue are estimated. ► Obtained data for optical parameters of mammary fibroadenoma at 0.63 μm are presented.