Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells

Transcriptome analysis showed that Lactobacillus acidophilus L-92 cells having anti-allergy effects on human up-regulated 41 genes involved permease, ABC transporter, proteinase and transcriptional regulator after attached to epithelial Caco-2 cells. Inversely, 37 genes were down-regulated, includin...

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Bibliographic Details
Published in:Journal of bioscience and bioengineering 2012-12, Vol.114 (6), p.582-585
Main Authors: Yanagihara, Sae, Hirota, Tatsuhiko, Yamamoto, Naoyuki
Format: Article
Language:English
Subjects:
ABC transporter
ABC transporters
Anti-allergy effect
ATP-Binding Cassette Transporters - genetics
Bacterial Adhesion - genetics
Biological and medical sciences
Biotechnology
Caco-2 Cells
Coculture Techniques
Down-Regulation
Epithelial Caco-2 cells
Fundamental and applied biological sciences. Psychology
Gene Expression Profiling
gene expression regulation
Gene Expression Regulation, Bacterial - genetics
genes
Genes, Bacterial - genetics
H+/K+-exchanging ATPase
human cell lines
Humans
Hypersensitivity - microbiology
Lactobacillus acidophilus
Lactobacillus acidophilus - cytology
Lactobacillus acidophilus - genetics
Lactobacillus acidophilus - physiology
Lactobacillus acidophilus L-92
Probiotic response
Probiotics
proteinases
transcription (genetics)
transcription factors
Transcription, Genetic - genetics
Transcriptome analysis
transcriptomics
Up-Regulation
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Summary:Transcriptome analysis showed that Lactobacillus acidophilus L-92 cells having anti-allergy effects on human up-regulated 41 genes involved permease, ABC transporter, proteinase and transcriptional regulator after attached to epithelial Caco-2 cells. Inversely, 37 genes were down-regulated, including ATP synthases, ABC transporters and transcriptional regulators.
ISSN:1389-1723
1347-4421
DOI:10.1016/j.jbiosc.2012.07.001