Diagnostic accuracy of serum brain derived neurotrophic factor concentration in antidepressant naieve patients with first major depression episode

Diagnosing major depressive disorder (MDD) continues to be based on meeting phenomenological and descriptive criteria. As of yet, there is still no non-invasive, peripheral biomarker that would allow for a certain diagnosis of MDD. The objective of this paper is to use the receiver operating charact...

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Bibliographic Details
Published in:Journal of psychiatric research 2013-02, Vol.47 (2), p.162-167
Main Authors: Karlovic, Dalibor, Serretti, Alessandro, Jevtovic, Sasa, Vrkic, Nada, Seric, Vesna, Peles, Alma Mihaljevic
Format: Article
Language:English
Subjects:
Antidepressants
biomarkers
Brain-derived neurotrophic factor
Depression
Neurotrophic factors
Online Access:Get full text
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Summary:Diagnosing major depressive disorder (MDD) continues to be based on meeting phenomenological and descriptive criteria. As of yet, there is still no non-invasive, peripheral biomarker that would allow for a certain diagnosis of MDD. The objective of this paper is to use the receiver operating characteristic (ROC) analysis to test the diagnostic value of serum concentrations of brain derived neurotrophic factor (BDNF) in diagnosing the first episode of MDD.
ISSN:0022-3956