Immune response after one or two doses of pandemic influenza A (H1N1) monovalent, AS03-adjuvanted vaccine in HIV infected adults

Highlights ► One dose of adjuvanted vaccine creates sufficient response in HIV infected patients. ► Two doses improve immunogenicity further. ► Response evaluated 4–9 months after immunization.

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Bibliographic Details
Published in:Vaccine 2012-11, Vol.30 (49), p.7067-7071
Main Authors: Nielsen, Allan Bybeck, Nielsen, Henriette Schjønning, Nielsen, Lars, Thybo, Søren, Kronborg, Gitte
Format: Article
Language:English
Subjects:
Adult
adults
Aged
Aged, 80 and over
Allergy and Immunology
alpha-Tocopherol - administration & dosage
Antibodies, Viral - blood
blood serum
Drug Combinations
Female
HIV
HIV infection
HIV infections
HIV Infections - immunology
Human immunodeficiency virus
Humans
Immune response
Immunization
Immunogenicity
Influenza
Influenza A Virus, H1N1 Subtype - immunology
Influenza Vaccines - administration & dosage
Influenza Vaccines - immunology
Influenza, Human - prevention & control
Male
Middle Aged
pandemic
Pandemic influenza A (H1N1)
Pandemics
patients
Polysorbates - administration & dosage
Public health
seroconversion
Squalene - administration & dosage
Studies
Vaccination
Vaccines
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Description
Summary:Highlights ► One dose of adjuvanted vaccine creates sufficient response in HIV infected patients. ► Two doses improve immunogenicity further. ► Response evaluated 4–9 months after immunization.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.09.052