Prevalence and associations of cataract in a rural Chinese adult population: the Handan Eye Study

Background Cataract remains the leading cause of blindness and visual impairment in the world and in China. However, data on the prevalence of cataract based on standardized lens grading protocols from mainland China are limited. This paper estimated the age- and gender-specific prevalence and risk...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2013, Vol.251 (1), p.203-212
Main Authors: Duan, Xin Rong, Liang, Yuan Bo, Wang, Ning Li, Wong, Tien Yin, Sun, Lan Ping, Yang, Xiao Hui, Tao, Qiu Shan, Yuan, Rui Zhi, Friedman, David S
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Aged
Asian Continental Ancestry Group - ethnology
Cataract - classification
Cataract - ethnology
Cataract Extraction - statistics & numerical data
China - epidemiology
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Miscellaneous
Ophthalmology
Prevalence
Risk Factors
Rural Population - statistics & numerical data
Sex Distribution
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Summary:Background Cataract remains the leading cause of blindness and visual impairment in the world and in China. However, data on the prevalence of cataract based on standardized lens grading protocols from mainland China are limited. This paper estimated the age- and gender-specific prevalence and risk factor for cataract Methods In a population-based Chinese sample, participants underwent a comprehensive ophthalmic examination, including assessment of cortical, nuclear, posterior subcapsular (PSC) and mixed lens opacities from slit-lamp grading using the Lens Opacities Classification System III. Results Of the 7,557 eligible subjects, 6,830 took part in the study (90.4 % response rate), and 6,544 participants (95.8 %, mean age 52.0 ± 11.8 years) had lens data for analyses. The prevalence of any cataract surgery in at least one eye was 0.8 % (95 % confidence interval [CI], 0.62, 1.06), with similar rates between men and women. The overall prevalence of any cataract or cataract surgery was 20.8 % (95 % CI, 19.8, 21.8), higher in women than in men after adjusting for age (23.6 % vs 17.6 %; OR: 1.78; 95 % CI: 1.54–2.07). When distinct lens opacity was categorized in each eye as cortical, nuclear, PSC or mixed, based on one randomly selected eye, cortical cataract was the most common distinct subtype (12.3 %), followed by mixed (3.2 %), nuclear (1.7 %), and PSC (0.2 %) cataract. The prevalence of all lens opacities increased with age ( P  
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-012-2012-x