Electron microscopy in the diagnosis of malignant fibrous histiocytoma of the lung presenting as metastasis to the maxillary gingiva

• Published in: International journal of oral and maxillofacial surgery 2013-01, Vol.42 (1), p.99-101
• Main Authors: Thomas, M.E, Koshi, R
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Bone Neoplasms - secondary; bone secondaries; Carcinoma, Large Cell - diagnosis; Dentistry; Dermatology; Diagnosis, Differential; electron microscopy; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Fatal Outcome; Fillipino; gingival lesions; gingival metastasis; Gingival Neoplasms - diagnosis; Gingival Neoplasms - secondary; Histiocytoma, Malignant Fibrous - secondary; Histiocytoma, Malignant Fibrous - ultrastructure; Humans; Liver Neoplasms - secondary; Lung Neoplasms - diagnosis; Lung Neoplasms - ultrastructure; Lymphatic Metastasis - pathology; Male; malignant fibrous histiocytoma; Maxilla - pathology; Medical sciences; Microscopy, Electron; Middle Aged; Otorhinolaryngology. Stomatology; Pneumology; pulmonary primary; soft tissue sarcoma; spindle celled tumours; Surgery; Tumors; Tumors of the respiratory system and mediastinum; Tumors of the skin and soft tissue. Premalignant lesions; ultrastructure
• ISSN: 0901-5027; 1399-0020
• DOI: 10.1016/j.ijom.2012.09.019

Abstract A rare case of an initial presentation of a metastatic lesion on the gingiva, arising from malignant fibrous histiocytoma (MFH) of the lung is reported. The role of electron microscopy in the diagnosis of soft tissue sarcomas has been studied. The ultrastructural details of a MFH are described and illustrated. The patient died within 9 weeks of the initial presentation with a gingival mass as is normal in these cases. He developed metastatic disease of the liver, lymph nodes, and bone. The role of electron microscopy in the diagnosis of soft tissue sarcomas is discussed.