Vitamin D for your patients with chronic hepatitis C?

Summary Vitamin D is increasingly becoming recognized as an important physiological regulator with pleiotropic functions outside of its classical role in skeletal homeostasis. A growing body of clinical evidence highlights the prevalence and risks of vitamin D deficiency in patients suffering from c...

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Bibliographic Details
Published in:Journal of hepatology 2013-01, Vol.58 (1), p.184-189
Main Authors: Rahman, Adeeb H, Branch, Andrea D
Format: Article
Language:English
Subjects:
1,25(OH)2D
25(OH)D
Bone Density Conservation Agents - therapeutic use
Bone Diseases - drug therapy
Gastroenterology and Hepatology
Hepatitis C
Hepatitis C, Chronic - drug therapy
Humans
Inflammation
Vitamin D
Vitamin D - therapeutic use
Vitamin D Deficiency - drug therapy
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Summary:Summary Vitamin D is increasingly becoming recognized as an important physiological regulator with pleiotropic functions outside of its classical role in skeletal homeostasis. A growing body of clinical evidence highlights the prevalence and risks of vitamin D deficiency in patients suffering from chronic hepatitis C infection, and vitamin D supplementation has been proposed as an adjunct to current standards of care. This review considers the experimental evidence for the anti-inflammatory, antifibrotic and antiviral effects of vitamin D, and discusses the therapeutic potential of vitamin D supplementation to protect against liver disease progression and improve responses to treatment.
ISSN:0168-8278
1600-0641
DOI:10.1016/j.jhep.2012.07.026