Sources of pertussis infection in young infants: A review of key evidence informing targeting of the cocoon strategy

Highlights► Literature review and pooled data analysis on infant pertussis infection sources. ► Parents were an important source of pertussis infection in very young infants. ► Grandparents were seldom implicated in infant pertussis infection. ► Siblings play a role as pertussis a source, but data i...

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Bibliographic Details
Published in:Vaccine 2013-01, Vol.31 (4), p.618-625
Main Authors: Wiley, K.E, Zuo, Y, Macartney, K.K, McIntyre, P.B
Format: Article
Language:English
Subjects:
Adult
adults
Age
Allergy and Immunology
Applied microbiology
Babies
Bacterial diseases
Biological and medical sciences
children
Confidence intervals
Contact
Contact Tracing
Data processing
Disease transmission
Ent and stomatologic bacterial diseases
epidemiological studies
Estimates
Families
Family Characteristics
fathers
Female
Fundamental and applied biological sciences. Psychology
grandparents
Human bacterial diseases
Humans
Immunisation
immunity
Immunization
income
Infant
Infants
Infection
Infections
Infectious diseases
Literature reviews
Male
Medical sciences
Microbiology
Morbidity
mothers
observational studies
Pertussis
Pertussis Vaccine - administration & dosage
Postpartum period
Reviews
siblings
Studies
Tetanus
Vaccination
Vaccine
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Whooping cough
Whooping Cough - epidemiology
Whooping Cough - prevention & control
Whooping Cough - transmission
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Summary:Highlights► Literature review and pooled data analysis on infant pertussis infection sources. ► Parents were an important source of pertussis infection in very young infants. ► Grandparents were seldom implicated in infant pertussis infection. ► Siblings play a role as pertussis a source, but data is heterogeneous. ► Parents should be the focus of post-partum pertussis immunisation.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.11.052