Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure

Background In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps. Objective To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in...

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Bibliographic Details
Published in:Dermatologic surgery 2013-01, Vol.39 (1pt1), p.43-50
Main Authors: Pauchot, Julien, Elkhyat, Ahmed, Rolin, Gwenael, Mac, Sophie, Grumblat, Anne, Fotso, Arnaud, Humbert, Philippe, Tropet, Yves
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Chondroitin Sulfates - therapeutic use
Collagen - therapeutic use
Elastin - therapeutic use
Head and Neck Neoplasms - surgery
Humans
Middle Aged
Otorhinolaryngologic Neoplasms - surgery
Reconstructive Surgical Procedures - methods
Retrospective Studies
Skin Neoplasms - surgery
Skin Transplantation - methods
Skin, Artificial
Surgical Flaps
Surgical Wound Infection - etiology
Time Factors
Wound Healing
Young Adult
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Summary:Background In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps. Objective To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in oncology. Patients and Method Retrospective, single‐center study involving 16 patients. Results Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinous areas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Wound healing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2. The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found over the tendinous areas. Conclusion The learning curve, the two‐stage graft required with DE2, and not using a vacuum‐assisted closure system can explain the high infection rate. The use of dermal equivalents is particularly indicated in the treatment of skin defect in oncology. The possibility of a one‐stage graft with DE1 and combination with negative pressure therapy is beneficial.
ISSN:1076-0512
1524-4725
DOI:10.1111/dsu.12044