The effect of bolus administration of tranexamic acid in revision hip arthroplasty

We assessed the efficacy of tranexamic acid in reducing transfusion requirements in patients undergoing revision hip arthroplasty. A prospective cohort study was designed comparing Tranexamic acid administration in 30 patients compared to 30 patients in a control group. Blood loss was measured in th...

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Bibliographic Details
Published in:Hip international 2012-11, Vol.22 (6), p.615-620
Main Authors: Kazi, Hussain A, Fountain, James R, Thomas, T Glyn, Carroll, Fintan A
Format: Article
Language:English
Subjects:
Aged
Antifibrinolytic Agents - therapeutic use
Arthroplasty, Replacement, Hip
Blood Loss, Surgical - prevention & control
Cohort Studies
Female
Humans
Male
Prospective Studies
Reoperation
Tranexamic Acid - therapeutic use
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Summary:We assessed the efficacy of tranexamic acid in reducing transfusion requirements in patients undergoing revision hip arthroplasty. A prospective cohort study was designed comparing Tranexamic acid administration in 30 patients compared to 30 patients in a control group. Blood loss was measured in theatre, pre- and postoperative haemoglobin measurements were recorded and postoperative haemodynamic parameters were evaluated. The mean postoperative haemoglobin was 9.5 g/dl in the tranexamic acid group and 8.2 g/dl in the control group (p
ISSN:1120-7000
1724-6067
DOI:10.5301/HIP.2012.10143