Risk Factors of Hypoparathyroidism Following Total Thyroidectomy for Thyroid Cancer

Background The risk factors responsible for hypoparathyroidism after total thyroidectomy have not been completely defined. The present study evaluated one surgeon’s personal experience of postoperative hypoparathyroidism after total thyroidectomy for thyroid cancer and predisposing risk factors of p...

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Bibliographic Details
Published in:World journal of surgery 2013-01, Vol.37 (1), p.94-101
Main Authors: Paek, Se Hyun, Lee, Young Mi, Min, Sun Young, Kim, Seok Won, Chung, Ki Wook, Youn, Yeo Kyu
Format: Article
Language:English
Subjects:
Abdominal Surgery
Adult
Cardiac Surgery
Causality
Female
General Surgery
Humans
Hypoparathyroidism
Hypoparathyroidism - epidemiology
Hypoparathyroidism - etiology
Male
Medicine
Medicine & Public Health
Middle Aged
Papillary Thyroid Carcinoma
Parathyroid Gland
Retrospective Studies
Risk Factors
Surgery
Thoracic Surgery
Thyroid Cancer
Thyroid Neoplasms - surgery
Thyroidectomy - adverse effects
Thyroidectomy - methods
Total Thyroidectomy
Vascular Surgery
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Summary:Background The risk factors responsible for hypoparathyroidism after total thyroidectomy have not been completely defined. The present study evaluated one surgeon’s personal experience of postoperative hypoparathyroidism after total thyroidectomy for thyroid cancer and predisposing risk factors of postoperative hypoparathyroidism. Methods We performed a retrospective analysis of 531 consecutive total thyroidectomy cases for thyroid cancer operated by single surgeon at the Center for Thyroid Cancer, National Cancer Center, Korea, from March 2003 to August 2006. Results Postoperative hypoparathyroidism occurred in 135 patients (25.4 %), 19 of whom (3.6 % of total patients) experienced permanent hypoparathyroidism. Parathyroid autotransplantation, bilateral central lymph node dissection, gross extrathyroidal extension, and the presence of parathyroid gland in the pathologic specimen were associated with postoperative hypoparathyroidism in multivariate analysis ( p  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-012-1809-4