Altered immune pathway activity under exercise challenge in Gulf War Illness: An exploratory analysis

Highlight ► Gulf War Illness (GWI) presents with decreased apoptotic and TNF-mediated signaling versus increased neurotransmission and NF-κB inflammatory activity.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2013-02, Vol.28, p.159-169
Main Authors: Broderick, Gordon, Ben-Hamo, Rotem, Vashishtha, Saurabh, Efroni, Sol, Nathanson, Lubov, Barnes, Zachary, Fletcher, Mary Ann, Klimas, Nancy
Format: Article
Language:English
Subjects:
Adult
Allergy and Immunology
Cytokines - analysis
Cytokines - physiology
Exercise - physiology
Exercise challenge
Fatigue Syndrome, Chronic - immunology
Fatigue Syndrome, Chronic - physiopathology
Flow Cytometry
Gene expression
Gene Expression - immunology
Gene Expression - physiology
Gulf War Illness
Humans
Immunity - immunology
Immunity - physiology
Leukocytes, Mononuclear - chemistry
Leukocytes, Mononuclear - immunology
Leukocytes, Mononuclear - physiology
Lymphocyte Subsets
Male
Mathematical immunology
Middle Aged
Oligonucleotide Array Sequence Analysis
Pathway activity
Persian Gulf Syndrome - immunology
Persian Gulf Syndrome - physiopathology
Psychiatry
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Description
Summary:Highlight ► Gulf War Illness (GWI) presents with decreased apoptotic and TNF-mediated signaling versus increased neurotransmission and NF-κB inflammatory activity.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2012.11.007