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Mortality and Morbidity in Extremely Low Birth Weight (ELBW) Infants in a Neonatal Intensive Care Unit
Objective To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU). Methods This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted du...
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| Published in: | Indian journal of pediatrics 2013, Vol.80 (1), p.16-20 |
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| container_title | Indian journal of pediatrics |
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| creator | Tagare, Amit Chaudhari, Sudha Kadam, Sandeep Vaidya, Umesh Pandit, Anand Sayyad, Mehmood G. |
| description | Objective
To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU).
Methods
This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted during this period were assessed for morbidities and interventions required during NICU stay and for their outcome like survival or death.
Results
The survival rate of 87 ELBW babies admitted during this period was 56.1 %. Pulmonary hemorrhage was the commonest cause of death (25 %) followed by respiratory distress syndrome (22.5 %), intraventricular hemorrhage (22.5 %) and sepsis (20 %). Significantly higher number of non-survivors were |
| doi_str_mv | 10.1007/s12098-012-0818-5 |
| format | article |
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To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU).
Methods
This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted during this period were assessed for morbidities and interventions required during NICU stay and for their outcome like survival or death.
Results
The survival rate of 87 ELBW babies admitted during this period was 56.1 %. Pulmonary hemorrhage was the commonest cause of death (25 %) followed by respiratory distress syndrome (22.5 %), intraventricular hemorrhage (22.5 %) and sepsis (20 %). Significantly higher number of non-survivors were <750 g at birth (
p
= 0.0001) and <28 wk gestation (
p
= 0.0001). Small for gestational babies had better chances of survival compared to those appropriate for gestational age (
p
= 0.005). RDS (67.8 %), probable sepsis (62.1 %) and hyperbilirubinemia (59.8 %) were the most frequent morbidities. Conventional ventilation (72.4 %) and nasal CPAP(48.3 %) were the commonest respiratory interventions. Surfactant replacement therapy was required in 47.1 % babies.
Conclusions
ELBW babies have a major contribution to mortality in a NICU. Babies with birth weight <750 g and gestation <28 wk have poor survival. RDS, pulmonary hemorrhage, IVH and sepsis are the common causes of death while RDS, sepsis and hyperbilirubinemia are the most common morbidities.</description><identifier>ISSN: 0019-5456</identifier><identifier>EISSN: 0973-7693</identifier><identifier>DOI: 10.1007/s12098-012-0818-5</identifier><identifier>PMID: 23150228</identifier><identifier>CODEN: IJPEA2</identifier><language>eng</language><publisher>India: Springer-Verlag</publisher><subject>Biological and medical sciences ; Diseases of mother, fetus and pregnancy ; Female ; General aspects ; Gynecology ; Gynecology. Andrology. Obstetrics ; Humans ; Infant Mortality ; Infant, Extremely Low Birth Weight ; Infant, Newborn ; Intensive Care Units, Neonatal ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Morbidity ; Original Article ; Pediatrics ; Pregnancy. Fetus. Placenta ; Prospective Studies ; Survival Analysis ; Survival Rate</subject><ispartof>Indian journal of pediatrics, 2013, Vol.80 (1), p.16-20</ispartof><rights>Dr. K C Chaudhuri Foundation 2012</rights><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-1d33152a8dd4ae6e9167f331549856c5153b595928d09ebe49e0218eb5bce6cf3</citedby><cites>FETCH-LOGICAL-c374t-1d33152a8dd4ae6e9167f331549856c5153b595928d09ebe49e0218eb5bce6cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4022,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27595063$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23150228$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tagare, Amit</creatorcontrib><creatorcontrib>Chaudhari, Sudha</creatorcontrib><creatorcontrib>Kadam, Sandeep</creatorcontrib><creatorcontrib>Vaidya, Umesh</creatorcontrib><creatorcontrib>Pandit, Anand</creatorcontrib><creatorcontrib>Sayyad, Mehmood G.</creatorcontrib><title>Mortality and Morbidity in Extremely Low Birth Weight (ELBW) Infants in a Neonatal Intensive Care Unit</title><title>Indian journal of pediatrics</title><addtitle>Indian J Pediatr</addtitle><addtitle>Indian J Pediatr</addtitle><description>Objective
To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU).
Methods
This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted during this period were assessed for morbidities and interventions required during NICU stay and for their outcome like survival or death.
Results
The survival rate of 87 ELBW babies admitted during this period was 56.1 %. Pulmonary hemorrhage was the commonest cause of death (25 %) followed by respiratory distress syndrome (22.5 %), intraventricular hemorrhage (22.5 %) and sepsis (20 %). Significantly higher number of non-survivors were <750 g at birth (
p
= 0.0001) and <28 wk gestation (
p
= 0.0001). Small for gestational babies had better chances of survival compared to those appropriate for gestational age (
p
= 0.005). RDS (67.8 %), probable sepsis (62.1 %) and hyperbilirubinemia (59.8 %) were the most frequent morbidities. Conventional ventilation (72.4 %) and nasal CPAP(48.3 %) were the commonest respiratory interventions. Surfactant replacement therapy was required in 47.1 % babies.
Conclusions
ELBW babies have a major contribution to mortality in a NICU. Babies with birth weight <750 g and gestation <28 wk have poor survival. RDS, pulmonary hemorrhage, IVH and sepsis are the common causes of death while RDS, sepsis and hyperbilirubinemia are the most common morbidities.</description><subject>Biological and medical sciences</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>General aspects</subject><subject>Gynecology</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant Mortality</subject><subject>Infant, Extremely Low Birth Weight</subject><subject>Infant, Newborn</subject><subject>Intensive Care Units, Neonatal</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Morbidity</subject><subject>Original Article</subject><subject>Pediatrics</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Prospective Studies</subject><subject>Survival Analysis</subject><subject>Survival Rate</subject><issn>0019-5456</issn><issn>0973-7693</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kEtP4zAURi3EiPcPYIO8QYJFBj9ix15CVR5SZ9hQdWk5yQ0YpQ7YLtB_P45aZnazsu_1uZ-vDkKnlPykhFRXkTKiVUEoK4iiqhA76IDoiheV1Hw33wnVhSiF3EeHMb4SwjSReg_tM04FYUwdoO7XEJLtXVpj61ucq9q1Y-U8nn6lAEvo13g2fOIbF9ILXoB7fkn4Yjq7WVziB99Zn-IIW_wbBm9zVu4m8NF9AJ7YAHjuXTpGPzrbRzjZnkdofjt9mtwXs8e7h8n1rGh4VaaCtjxvxqxq29KCBE1l1Y2tUishG0EFr4UWmqmWaKih1EAYVVCLugHZdPwIXWxy38LwvoKYzNLFBvreehhW0VBWcam1oiyjdIM2YYgxQGfeglvasDaUmFGv2eg1Wa8Z9RqRZ8628at6Ce3fiW-fGTjfAjY2tu-C9Y2L_7gqb08kzxzbcDE_-WcI5nVYBZ_V_Of3PzZ3kK0</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Tagare, Amit</creator><creator>Chaudhari, Sudha</creator><creator>Kadam, Sandeep</creator><creator>Vaidya, Umesh</creator><creator>Pandit, Anand</creator><creator>Sayyad, Mehmood G.</creator><general>Springer-Verlag</general><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2013</creationdate><title>Mortality and Morbidity in Extremely Low Birth Weight (ELBW) Infants in a Neonatal Intensive Care Unit</title><author>Tagare, Amit ; Chaudhari, Sudha ; Kadam, Sandeep ; Vaidya, Umesh ; Pandit, Anand ; Sayyad, Mehmood G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-1d33152a8dd4ae6e9167f331549856c5153b595928d09ebe49e0218eb5bce6cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Biological and medical sciences</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>General aspects</topic><topic>Gynecology</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant Mortality</topic><topic>Infant, Extremely Low Birth Weight</topic><topic>Infant, Newborn</topic><topic>Intensive Care Units, Neonatal</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Morbidity</topic><topic>Original Article</topic><topic>Pediatrics</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Prospective Studies</topic><topic>Survival Analysis</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tagare, Amit</creatorcontrib><creatorcontrib>Chaudhari, Sudha</creatorcontrib><creatorcontrib>Kadam, Sandeep</creatorcontrib><creatorcontrib>Vaidya, Umesh</creatorcontrib><creatorcontrib>Pandit, Anand</creatorcontrib><creatorcontrib>Sayyad, Mehmood G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Indian journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tagare, Amit</au><au>Chaudhari, Sudha</au><au>Kadam, Sandeep</au><au>Vaidya, Umesh</au><au>Pandit, Anand</au><au>Sayyad, Mehmood G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality and Morbidity in Extremely Low Birth Weight (ELBW) Infants in a Neonatal Intensive Care Unit</atitle><jtitle>Indian journal of pediatrics</jtitle><stitle>Indian J Pediatr</stitle><addtitle>Indian J Pediatr</addtitle><date>2013</date><risdate>2013</risdate><volume>80</volume><issue>1</issue><spage>16</spage><epage>20</epage><pages>16-20</pages><issn>0019-5456</issn><eissn>0973-7693</eissn><coden>IJPEA2</coden><abstract>Objective
To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU).
Methods
This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted during this period were assessed for morbidities and interventions required during NICU stay and for their outcome like survival or death.
Results
The survival rate of 87 ELBW babies admitted during this period was 56.1 %. Pulmonary hemorrhage was the commonest cause of death (25 %) followed by respiratory distress syndrome (22.5 %), intraventricular hemorrhage (22.5 %) and sepsis (20 %). Significantly higher number of non-survivors were <750 g at birth (
p
= 0.0001) and <28 wk gestation (
p
= 0.0001). Small for gestational babies had better chances of survival compared to those appropriate for gestational age (
p
= 0.005). RDS (67.8 %), probable sepsis (62.1 %) and hyperbilirubinemia (59.8 %) were the most frequent morbidities. Conventional ventilation (72.4 %) and nasal CPAP(48.3 %) were the commonest respiratory interventions. Surfactant replacement therapy was required in 47.1 % babies.
Conclusions
ELBW babies have a major contribution to mortality in a NICU. Babies with birth weight <750 g and gestation <28 wk have poor survival. RDS, pulmonary hemorrhage, IVH and sepsis are the common causes of death while RDS, sepsis and hyperbilirubinemia are the most common morbidities.</abstract><cop>India</cop><pub>Springer-Verlag</pub><pmid>23150228</pmid><doi>10.1007/s12098-012-0818-5</doi><tpages>5</tpages></addata></record> |
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| ispartof | Indian journal of pediatrics, 2013, Vol.80 (1), p.16-20 |
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| source | Springer Nature |
| subjects | Biological and medical sciences Diseases of mother, fetus and pregnancy Female General aspects Gynecology Gynecology. Andrology. Obstetrics Humans Infant Mortality Infant, Extremely Low Birth Weight Infant, Newborn Intensive Care Units, Neonatal Male Medical sciences Medicine Medicine & Public Health Morbidity Original Article Pediatrics Pregnancy. Fetus. Placenta Prospective Studies Survival Analysis Survival Rate |
| title | Mortality and Morbidity in Extremely Low Birth Weight (ELBW) Infants in a Neonatal Intensive Care Unit |
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