Influence of HbA1c levels on platelet function profiles associated with tight glycemic control in patients presenting with hyperglycemia and an acute coronary syndrome: A subanalysis of the CHIPS Study (“Control deHIperglucemia y ActividadPlaquetaria en Pacientes conSíndrome Coronario Agudo”)

Patients with hyperglycemia, an acute coronary syndrome and poor glycemic control have increased platelet reactivity and poor prognosis. However, it is unclear the influence of a tight glycemic control on platelet reactivity in these patients. This is a subanalysis of the CHIPS study. This trial ran...

Full description

Saved in:
Bibliographic Details
Published in:Journal of thrombosis and thrombolysis 2013-02, Vol.35 (2), p.165-174
Main Authors: Vivas, David, García-Rubira, Juan C., Bernardo, Esther, Angiolillo, Dominick J., Martín, Patricia, Calle-Pascual, Alfonso, Núñez-Gil, Iván, Macaya, Carlos, Fernández-Ortiz, Antonio
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - blood
Acute Coronary Syndrome - diagnosis
Acute Coronary Syndrome - epidemiology
Aged
Aged, 80 and over
Biomarkers - blood
Blood Glucose - metabolism
Cardiology
Female
Glycated Hemoglobin A - biosynthesis
Glycated Hemoglobin A - physiology
Glycemic Index - physiology
Hematology
Humans
Hyperglycemia - blood
Hyperglycemia - diagnosis
Hyperglycemia - epidemiology
Male
Medicine
Medicine & Public Health
Middle Aged
Platelet Aggregation - physiology
Platelet Function Tests - methods
Prospective Studies
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Patients with hyperglycemia, an acute coronary syndrome and poor glycemic control have increased platelet reactivity and poor prognosis. However, it is unclear the influence of a tight glycemic control on platelet reactivity in these patients. This is a subanalysis of the CHIPS study. This trial randomized patients with hyperglycemia to undergo an intensive glucose control (target blood glucose 80–120 mg/dL), or conventional glucose control (target blood glucose
ISSN:0929-5305
1573-742X
DOI:10.1007/s11239-012-0834-3