Changes in heart rate variability during TOVA testing in patients with major depressive disorder

Aim The aim of this study was to identify major depressive disorder (MDD) based on heart rate variability (HRV) during tests of variables of attention (TOVA). Method Forty‐five MDD patients without cardiovascular disease and 45 controls matched by age and gender participated in this study. Results C...

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Bibliographic Details
Published in:Psychiatry and clinical neurosciences 2013-01, Vol.67 (1), p.35-40
Main Authors: Shen, Tsu‐Wang, Liu, Fang‐Chih, Chen, Shaw‐Ji, Chen, Shao‐Tsu
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Anxiety
Attention - physiology
autonomic nervous system
Autonomic Nervous System - physiopathology
Biological and medical sciences
Depression
Depressive Disorder, Major - physiopathology
Female
Heart rate
Heart Rate - physiology
heart rate variability
Humans
major depressive disorder
Male
Medical sciences
Middle Aged
Mood disorders
Neuropsychological Tests
Psychiatric Status Rating Scales
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Reaction Time - physiology
test of variables of attention
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Summary:Aim The aim of this study was to identify major depressive disorder (MDD) based on heart rate variability (HRV) during tests of variables of attention (TOVA). Method Forty‐five MDD patients without cardiovascular disease and 45 controls matched by age and gender participated in this study. Results Compared to the controls, the MDD group had lower resting HRV parameters, more omissions and variability and longer response times on TOVA, and failure of attention employment to decrease HRV. Conclusions The resting HRV parameters may provide easily measured, clinically useful ways to identify patients with MDD and to monitor their progress in treatment.
ISSN:1323-1316
1440-1819
DOI:10.1111/j.1440-1819.2012.02404.x