Prostate‐specific antigen concentration in young men: new estimates and review of the literature

Study Type – Diagnostic (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Although non‐recommended PSA testing has been reported in men younger than 40 years of age, there are few recognized data on PSA in younger American men, particularly younger African‐...

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Bibliographic Details
Published in:BJU international 2012-12, Vol.110 (11), p.1627-1635
Main Authors: Sutcliffe, Siobhan, Pakpahan, Ratna, Sokoll, Lori J., Elliott, Debra J., Nevin, Remington L., Cersovsky, Steven B., Walsh, Patrick C., Platz, Elizabeth A.
Format: Article
Language:English
Subjects:
Adult
African Americans
Age
Antigens
Biological and medical sciences
Caucasian race
Cohort Studies
Estimates
European Continental Ancestry Group
Humans
Male
Medical sciences
Nephrology. Urinary tract diseases
Prostate cancer
Prostate-Specific Antigen - blood
prostate‐specific antigen
Prostatic Neoplasms - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - ethnology
Reference Values
review
United States - ethnology
White people
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Summary:Study Type – Diagnostic (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Although non‐recommended PSA testing has been reported in men younger than 40 years of age, there are few recognized data on PSA in younger American men, particularly younger African‐American men, to provide age‐ and race‐specific references. Using data from an existing large study of young, male members of the US military, aged 28–36 years, the present study provides PSA reference distributions for young Caucasian‐American men (median = 0.56, 95th percentile = 1.42, range:
ISSN:1464-4096
1464-410X
DOI:10.1111/j.1464-410X.2012.11111.x