Positron emission tomography with fluorine-deoxyglucose in sarcomas and non-sarcoma non-epithelial tumors

The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined. To report a Chilean experience with NSNE tumors evaluated using PET with FDG. Retrospective review of the database of a PET laborator...

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Bibliographic Details
Published in:Revista medíca de Chile 2012-09, Vol.140 (9), p.1116-1125
Main Authors: Massardo, Teresa, Jofré, María Josefina, Sierralta, María Paulina, Canessa, José, Castro, Gabriel, Berrocal, Isabel, Gallegos, Iván
Format: Article
Language:Spanish
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Fluorodeoxyglucose F18
Humans
Male
Middle Aged
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Radiopharmaceuticals
Retrospective Studies
Sarcoma - diagnostic imaging
Young Adult
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Summary:The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined. To report a Chilean experience with NSNE tumors evaluated using PET with FDG. Retrospective review of the database of a PET laboratory. Demographic data, indications and metabolic findings were compared with conventional imaging in 88 adults and children with diverse bone and soft tissue sarcomas as well as 24 gastrointestinal stromal tumors (GIST), 6 pleural malignant mesotheliomas in adults, and 9 medulloblastomas in children. FDG showed good concordance with conventional imaging in NSNE tumors. It was helpful for staging, restaging, follow-up after treatment and for the detection of new not previously suspected lesions. PET with FDG could have a prognostic role and help in patient management, mainly in musculoskeletal and high grade or less differentiated sarcomas. In GIST, it was a good tool for immunotherapy control.
ISSN:0717-6163
DOI:10.4067/S0034-98872012000900003