Magnetic nanoparticles as new diagnostic tools in medicine

Magnetic iron oxide nanoparticles have raised much interest during the recent years due to their novel properties (superpara-magnetism, high saturation field, blocking temperature, etc.) and potential applications in organic synthesis, biotechnology and finally in medicine. The medicinal application...

Full description

Saved in:
Bibliographic Details
Published in:Advances in medical sciences 2012-12, Vol.57 (2), p.196-207
Main Authors: Niemirowicz, K, Markiewicz, KH, Wilczewska, AZ, Car, H
Format: Article
Language:English
Subjects:
Animals
Bacteria - isolation & purification
Contrast Media
DNA - genetics
DNA - isolation & purification
Humans
Immobilized Proteins
Lymphography - methods
magnetic immobilization of proteins
magnetic nanoparticles
magnetic resonance imaging
Magnetic Resonance Imaging - methods
magnetic separation pathogens
magnetic separations of DNA
Magnetite Nanoparticles
Nanotechnology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Magnetic iron oxide nanoparticles have raised much interest during the recent years due to their novel properties (superpara-magnetism, high saturation field, blocking temperature, etc.) and potential applications in organic synthesis, biotechnology and finally in medicine. The medicinal applications include: controlled drug delivery systems (DDS), magnetic resonance imaging (MRI), magnetic fluid hyperthermia (MFH), macromolecules and pathogens separation, cancer therapy and so on. In this paper we would like to present the newest literature reports concerning usage of MNPs in medicinal diagnostics such as: –magnetic separations of DNA (immobilization, isolation, diagnosis of genetic disorders and detection of exogenous substances in the organisms)–magnetic immobilization of proteins (applications in biotechnology, medicine, and catalysis)–magnetic separations of pathogens (i.e. isolation of bacteria, detection of various pathogens)–magnetic resonance imaging (imaging contrast agents, lymphangiography).
ISSN:1896-1126
1898-4002
DOI:10.2478/v10039-012-0031-9