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Hydrogen-Free Alkene Reduction in Continuous Flow

The first continuous hydrogenation that requires neither H2 nor metal catalysis generates diimide by a novel reagent combination. The simple flow reactor employed minimizes residence time by enabling safe operation at elevated temperature.

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Bibliographic Details
Published in:Organic letters 2013-02, Vol.15 (3), p.710-713
Main Authors: Kleinke, Andrew S, Jamison, Timothy F
Format: Article
Language:English
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Summary:The first continuous hydrogenation that requires neither H2 nor metal catalysis generates diimide by a novel reagent combination. The simple flow reactor employed minimizes residence time by enabling safe operation at elevated temperature.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol400051n