Doppler Ultrasonographic Assessment of Early Changes in Kidney Graft Size and Resistive Index and Their Predictive Role on 1-Year Graft Function

• Published in: Transplantation proceedings 2013, Vol.45 (1), p.172-174
• Main Authors: Mohammadi, A, Biniaz, F, Nikoobakht, M.R, Barbari, G.R
• Format: Article
• Language: English
• Subjects: Adult; Female; Follow-Up Studies; Graft Survival; Humans; Kidney - diagnostic imaging; Kidney - pathology; Kidney Failure, Chronic - diagnostic imaging; Kidney Failure, Chronic - mortality; Kidney Failure, Chronic - surgery; Kidney Transplantation - methods; Living Donors; Male; Middle Aged; Postoperative Period; Predictive Value of Tests; Surgery; Time Factors; Transplantation, Homologous; Treatment Outcome; Ultrasonography, Doppler - methods; Young Adult
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2012.08.016

Abstract Introduction Doppler ultrasonography is a simple, noninvasive diagnostic tool for assessment and follow-up studies in renal transplantation. The aim of this study was to investigate the correlation between early changes in graft size and resistive index (RI) and 1-year graft function. Method We recorded graft size, RI, and serum creatinine level in 25 living kidney donors (before transplantation) as well as early (1-week), and 1-year after transplantation (in kidney recipients). Then we assessed the correlation between early changes in graft size and RI and 1-year Scr. Results Repeated measurement tests showed a significant increase in graft size including length (initial, 107.6 ± 5.8 mm; average increase, 8.48 ± 5.61 mm; P < 0.001), anterior-posterior diameter (initial, 46.3 ± 4.7 mm; average increase, 6.16 ± 4.08 mm; P < 0.001), and parenchymal thickness (initial, 14.96 ± 2.1 mm; average increase, 3.04 ± 1.98 mm; P < 0.001) 1 week after transplantation. However, during the 1-year follow-up examinations the increase in graft size was not significant in contrast with 1-week follow-up values ( P > 0.47). Pearson correlations showed significant correlation between early changes in graft size (eg, anterior-posterior diameter, r = −0.492; P = 0.013); and 1-year Scr levels. There was no significant correlation between graft size changes and RI or RI and Scr early or 1-year after transplantation. Conclusion There was a significant increase in kidney size (including length, anterior-posterior diameter, and cortical thickness) early after transplantation. The amount of increase in size significantly correlated with Scr level 1-year after transplantation. There was no correlation between RI and Scr.