Impact of Ectopic Insertion on Treatment Outcome of Primary Non-refluxing Megaureter

Objective To investigate the characteristics of primary non-refluxing megaureter with ectopic insertion and its effects on renal function. Methods Of 118 patients diagnosed with primary non-refluxing megaureter, we retrospectively studied 33 patients who underwent surgical treatment. Depending on th...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2013-02, Vol.81 (2), p.402-406
Main Authors: Im, Young Jae, Jung, Hyun Jin, Lee, Yong Seung, Hong, Chang Hee, Han, Sang Won
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child
Child, Preschool
Dilatation, Pathologic - complications
Dilatation, Pathologic - diagnosis
Dilatation, Pathologic - surgery
Female
Humans
Hydronephrosis - etiology
Hydronephrosis - physiopathology
Hydronephrosis - surgery
Infant
Kidney - physiopathology
Male
Malformations of the urinary system
Medical sciences
Nephrology. Urinary tract diseases
Organ Size
Retrospective Studies
Treatment Outcome
Ureter - abnormalities
Ureter - pathology
Ureter - surgery
Ureteral Diseases - complications
Ureteral Diseases - diagnosis
Ureteral Diseases - surgery
Urinary system involvement in other diseases. Miscellaneous
Urinary tract. Prostate gland
Urology
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Summary:Objective To investigate the characteristics of primary non-refluxing megaureter with ectopic insertion and its effects on renal function. Methods Of 118 patients diagnosed with primary non-refluxing megaureter, we retrospectively studied 33 patients who underwent surgical treatment. Depending on the position of ureteral insertion, patients were classified as having either an ectopic or orthotopic megaureter; clinical characteristics and renal function, were analyzed. Results Among the 36 primary non-refluxing megaureters, 7 (19.4%) had ectopic megaureter. A total of 34.5% of the orthotopic megaureter and all ectopic megaureter cases were women ( P  = .003). The mean value of maximum ureteral diameter was significantly wider for ectopic than for orthotopic megaureter (16.3 vs 12.1 mm, respectively, P  = .029). Mean preoperative differential renal function (DRF) were 36.4% and 43.0% for ectopic and orthotopic megaureters, respectively ( P  = .164). After surgery, the mean DRF of ectopic megaureter had decreased from 50% to 18.8%, whereas the mean DRF of orthotopic megaureter was 42.9% ( P  
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2012.11.038