Search for Conserved Secondary Structures of RNA

We suggest a new algorithm to search a given set of the RNA sequences for conserved secondary structures. The algorithm is based on alignment of the sequences for potential helical strands. This procedure can be used to search for new structured RNAs and new regulatory elements. It is efficient for...

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Bibliographic Details
Published in:Molecular biology (New York) 2003-09, Vol.37 (5), p.723-732
Main Authors: Gorbunov, K Yu, Mironov, A A, Lyubetsky, V A
Format: Article
Language:English
Subjects:
Ribonucleic acid
RNA
Online Access:Get full text
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Summary:We suggest a new algorithm to search a given set of the RNA sequences for conserved secondary structures. The algorithm is based on alignment of the sequences for potential helical strands. This procedure can be used to search for new structured RNAs and new regulatory elements. It is efficient for the genome-scale analysis. The results of various tests run with this algorithm are shown.[PUBLICATION ABSTRACT]
ISSN:0026-8933
1608-3245
DOI:10.1023/A:1026089011336