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Recent progress in biocatalysis using supercritical carbon dioxide
The latest advances in biocatalysis using supercritical carbon dioxide (scCO2) are reviewed. Stability and stabilization methodologies of enzymes in scCO2 as well as reactions for organic synthesis are described. Especially, varieties of examples for lipase-catalyzed synthesis of chiral compounds us...
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Published in: | Journal of bioscience and bioengineering 2013-03, Vol.115 (3), p.233-241 |
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container_title | Journal of bioscience and bioengineering |
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creator | Matsuda, Tomoko |
description | The latest advances in biocatalysis using supercritical carbon dioxide (scCO2) are reviewed. Stability and stabilization methodologies of enzymes in scCO2 as well as reactions for organic synthesis are described. Especially, varieties of examples for lipase-catalyzed synthesis of chiral compounds using scCO2 are given. Furthermore, asymmetric reduction by alcohol dehydrogenase in scCO2 and carboxylation by decarboxylase in scCO2 are also introduced. |
doi_str_mv | 10.1016/j.jbiosc.2012.10.002 |
format | article |
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Hemisynthesis ; Biological and medical sciences ; Biotechnology ; Candida antarctica lipase B ; Carbon dioxide ; Carbon Dioxide - chemistry ; carboxylation ; Chemistry Techniques, Synthetic ; decarboxylases ; Enzyme ; Enzyme Stability ; Fundamental and applied biological sciences. Psychology ; Geotrichum candidum ; Lipase - metabolism ; lipases ; Methods. Procedures. Technologies ; Novozym 435 ; Organic synthesis ; Solvents - chemistry ; Supercritical fluid</subject><ispartof>Journal of bioscience and bioengineering, 2013-03, Vol.115 (3), p.233-241</ispartof><rights>2012 The Society for Biotechnology, Japan</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. 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Hemisynthesis</subject><subject>Biological and medical sciences</subject><subject>Biotechnology</subject><subject>Candida antarctica lipase B</subject><subject>Carbon dioxide</subject><subject>Carbon Dioxide - chemistry</subject><subject>carboxylation</subject><subject>Chemistry Techniques, Synthetic</subject><subject>decarboxylases</subject><subject>Enzyme</subject><subject>Enzyme Stability</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Geotrichum candidum</subject><subject>Lipase - metabolism</subject><subject>lipases</subject><subject>Methods. Procedures. 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Hemisynthesis</topic><topic>Biological and medical sciences</topic><topic>Biotechnology</topic><topic>Candida antarctica lipase B</topic><topic>Carbon dioxide</topic><topic>Carbon Dioxide - chemistry</topic><topic>carboxylation</topic><topic>Chemistry Techniques, Synthetic</topic><topic>decarboxylases</topic><topic>Enzyme</topic><topic>Enzyme Stability</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Geotrichum candidum</topic><topic>Lipase - metabolism</topic><topic>lipases</topic><topic>Methods. Procedures. 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subjects | Alcohol dehydrogenase Alcohol Dehydrogenase - metabolism Asymmetric synthesis Biocatalysis Bioconversions. Hemisynthesis Biological and medical sciences Biotechnology Candida antarctica lipase B Carbon dioxide Carbon Dioxide - chemistry carboxylation Chemistry Techniques, Synthetic decarboxylases Enzyme Enzyme Stability Fundamental and applied biological sciences. Psychology Geotrichum candidum Lipase - metabolism lipases Methods. Procedures. Technologies Novozym 435 Organic synthesis Solvents - chemistry Supercritical fluid |
title | Recent progress in biocatalysis using supercritical carbon dioxide |
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