Communication between gastrointestinal bacteria and the nervous system

Graphical abstract. Highlights ► Gut microbiota is a new target for the treatment of intestinal disorders. ► Modulation of microbiota has an impact on animal behaviour. ► Probiotics have important effects on gut and mental health. ► Intestinal microbiota could be a new target for mental illness. ► P...

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Bibliographic Details
Published in:Current opinion in pharmacology 2012-12, Vol.12 (6), p.667-672
Main Authors: Bravo, Javier A, Julio-Pieper, Marcela, Forsythe, Paul, Kunze, Wolfgang, Dinan, Timothy G, Bienenstock, John, Cryan, John F
Format: Article
Language:English
Subjects:
Adjuvants
Animals
Anxiety - drug therapy
Anxiety - microbiology
Central Nervous System - microbiology
Central Nervous System - physiopathology
Depression - drug therapy
Depression - microbiology
Gastrointestinal Diseases - drug therapy
Gastrointestinal Diseases - microbiology
Gastrointestinal Diseases - physiopathology
Gastrointestinal Tract - microbiology
Gastrointestinal Tract - physiopathology
Humans
Internal Medicine
Irritable Bowel Syndrome - drug therapy
Irritable Bowel Syndrome - microbiology
Irritable Bowel Syndrome - physiopathology
Medical Education
Probiotics - therapeutic use
Stress, Psychological - drug therapy
Stress, Psychological - microbiology
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Summary:Graphical abstract. Highlights ► Gut microbiota is a new target for the treatment of intestinal disorders. ► Modulation of microbiota has an impact on animal behaviour. ► Probiotics have important effects on gut and mental health. ► Intestinal microbiota could be a new target for mental illness. ► Probiotics could be novel adjuvant to psychiatric therapy.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2012.09.010