Cost-effectiveness of childhood influenza vaccination in England and Wales: Results from a dynamic transmission model

Highlights ► The economics of vaccinate pre-school age children and/or school age children was assessed. ► Vaccinating 2–18 year olds was estimated to be the most cost-effective policy. ► The mean ICER for this policy was estimated at £251/QALY relative to current practice. ► Paediatric vaccination...

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Bibliographic Details
Published in:Vaccine 2013-01, Vol.31 (6), p.927-942
Main Authors: Pitman, R.J, Nagy, L.D, Sculpher, M.J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Age Factors
Aged
Aged, 80 and over
Allergy and Immunology
Applied microbiology
Biological and medical sciences
Child
Child, Preschool
childhood
children
Cost-Benefit Analysis
Cost-effectiveness
Costs
elderly
England
England - epidemiology
Epidemiologic Methods
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Health services
herds
Humans
Illnesses
immunity
Infant
Infections
Influenza
Influenza Vaccines - administration & dosage
Influenza Vaccines - economics
Influenza Vaccines - immunology
Influenza, Human - economics
Influenza, Human - epidemiology
Influenza, Human - prevention & control
Influenza, Human - transmission
issues and policy
Male
Mathematical model
Microbiology
Middle Aged
Paediatric
Pneumonia
Population
quality-adjusted life year
Seasonal
Studies
Transmission model
Vaccination
Vaccination - economics
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Wales
Wales - epidemiology
Young Adult
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Summary:Highlights ► The economics of vaccinate pre-school age children and/or school age children was assessed. ► Vaccinating 2–18 year olds was estimated to be the most cost-effective policy. ► The mean ICER for this policy was estimated at £251/QALY relative to current practice. ► Paediatric vaccination would appear to be a highly cost-effective intervention.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.12.010