A Registry of Adult African American Twins: The Carolina African American Twin Study of Aging

Twin studies have seldom addressed ethnicity as one of the possible factors that create unique combinations of genetic and environmental influences. The major objective of the Carolina African American Twin Study of Aging is to identify the proportion of the genetic and environmental sources of indi...

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Bibliographic Details
Published in:Twin research and human genetics 2013-02, Vol.16 (1), p.476-480
Main Author: Whitfield, Keith E.
Format: Article
Language:English
Subjects:
Adult
African Americans
African Americans - genetics
Age Factors
Aged
Aged, 80 and over
Aging
Aging - genetics
Aging - pathology
Cohort Studies
Diseases in Twins - epidemiology
Diseases in Twins - genetics
Epidemiologic Research Design
Female
Gene-Environment Interaction
Genealogy
Genetics, Behavioral
Health Status
Humans
Male
Middle Aged
North Carolina - epidemiology
Patient Selection
Psychology
Registries
Twins
Twins, Dizygotic - genetics
Twins, Monozygotic - genetics
Young Adult
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Summary:Twin studies have seldom addressed ethnicity as one of the possible factors that create unique combinations of genetic and environmental influences. The major objective of the Carolina African American Twin Study of Aging is to identify the proportion of the genetic and environmental sources of individual variation in measures of health and behavioral factors in a sample of adult African Americans. Drawn from birth records from the State of North Carolina, this in-person study used public records to identify a cohort of twins between 22 and 92 years of age (X = 49.82 yrs, SD = 14.62), 39.7% of which were men. Members of non-intact twin pairs and siblings were also recruited to explore alternative models to the classic twin design. To date, the project has contributed to knowledge about blood pressure, forced expiratory volume, chronic illness, body mass index, and waist-hip ratio memory, personality, social, and demographic factors, mortality, and mental health.
ISSN:1832-4274
1839-2628
DOI:10.1017/thg.2012.79