Molecular epidemiological typing of enteropathogenic Escherichia coli strains from Australian patients

Abstract Enteropathogenic Escherichia coli (EPEC) are an important cause of diarrhoea worldwide, particularly in children. Sixty-one EPEC strains isolated from stool specimens of symptomatic persons from 2008 to 2011 were characterised for the prevalence of diarrhoea-associated putative virulence ge...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2013-03, Vol.75 (3), p.320-324
Main Authors: Staples, Megan, Doyle, Christine J, Graham, Rikki M.A, Jennison, Amy V
Format: Article
Language:English
Subjects:
Australia - epidemiology
Bacterial Typing Techniques - methods
Characterisation
Diarrhea - microbiology
Enteropathogenic Escherichia coli - classification
Enteropathogenic Escherichia coli - genetics
Enteropathogenic Escherichia coli - isolation & purification
EPEC
Escherichia coli
Escherichia coli Proteins - genetics
Feces - microbiology
Genes, Bacterial
Genetic Variation
Humans
Infectious Disease
Internal Medicine
Molecular Epidemiology
Multilocus Sequence Typing - methods
Phylogeny
Prevalence
Virulence
Virulence Factors - genetics
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Summary:Abstract Enteropathogenic Escherichia coli (EPEC) are an important cause of diarrhoea worldwide, particularly in children. Sixty-one EPEC strains isolated from stool specimens of symptomatic persons from 2008 to 2011 were characterised for the prevalence of diarrhoea-associated putative virulence genes. Phylogenetic typing, serotyping, multilocus variable-number repeat analysis (MLVA), and multilocus sequence typing (MLST) were also performed. The EPEC isolates were highly heterogeneous, representing all 4 phylogenetic groups and comprising 59 MLVA types, 49 MLST types, and 43 serotypes. This diversity is indicative of the complexity of the human enteric EPEC population, which may be either commensal or pathogenic.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2012.11.010