The effect of acute café latte ingestion on fasting serum lipid levels in healthy individuals

• Published in: Journal of clinical lipidology 2013-03, Vol.7 (2), p.165-168
• Main Authors: Zargar, Atanaz, PharmD, BCPS, Auttapibarn, Clint, BS, Hong, Sung Hee, BS, Larson, Tyler J., BS, Hayworth, Katelyn H., BS, Ito, Matthew K., PharmD, FCCP, FNLA
• Format: Article
• Language: English
• Subjects: Adult; Blood Glucose - analysis; Blood Glucose - drug effects; Café latte; Cardiovascular; Cholesterol; Cholesterol - blood; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Cholesterol, LDL - drug effects; Coffee; Coffee - chemistry; Eating; Fasting; Female; Gluscose; Humans; LDL cholesterol; Lipid panel; Lipids - blood; Male; Middle Aged; Plant Extracts - chemistry; Plant Extracts - pharmacology; Prospective Studies; Triglycerides - blood
• ISSN: 1933-2874; 1876-4789
• DOI: 10.1016/j.jacl.2012.11.001

Background Many patients drink café latte as part of their habitual morning routine to start their day and may be unable to skip this step before drawing a fasting blood sample for cholesterol testing. However, it is unknown what the acute effects of consuming a café latte are on fasting serum lipids just before blood sampling. Objective This was a prospective, open-label study with the primary objective of evaluating the acute effect of a 12-oz café latte (2% milk) on calculated low-density lipoprotein cholesterol (LDL-C) and secondary objectives of triglyceride, total cholesterol, high-density lipoprotein cholesterol (HDL-C), non-HDL-C, and fasting blood glucose (FBG). Methods A 10-hour fasting lipid profile was obtained before and 30 minutes after subjects consumed the café latte. Results Forty-nine adult participants (34 females; age [mean ± SD] 32.2 ± 13.2 years) were studied. No significant changes in total cholesterol, LDL-C, or non-HDL-C were observed after coffee consumption. Triglyceride significantly decreased from a median of 76.0 to 75.0 mg/dL ( P  = .002). HDL-C and FBG increased from a mean of 54.4 ± 12.7 to 56.4 ± 14.5 mg/dL ( P  = .015) and 87.2 ± 7.0 to 97.3 ± 12.9 mg/dL ( P < .001), respectively. Conclusion Consumption of 12 oz. of café latte within one hour of blood draw did not result in a significant change in LDL-C or non-HDL-C in young, nonobese healthy individuals. However, FBG levels increased by almost 12%.